Linear mixed models for cognition and behavioural disturbances
| Parameter | Estimate | 95% CI | Sig |
| Cognition | |||
| Intercept* | 45.52 | 41.02 to 50.02 | <0.001 |
| Time effect† | −0.43 | −0.49 to −0.38 | <0.001 |
| Psychosis | −1.26 | −1.74 to −0.78 | <0.001 |
| CAG | −0.32 | −0.40 to −0.24 | <0.001 |
| Age | −0.08 | −0.11 to −0.06 | <0.001 |
| Sex (female) | −0.41 | −0.86 to 0.03 | 0.070 |
| Behavioural Disturbances‡ | |||
| Intercept§ | 25.46 | 10.75 to 40.17 | 0.001 |
| Time effect¶ | 0.00 | −0.17 to 0.16 | 0.959 |
| Psychosis | 8.55 | 6.72 to 10.39 | <0.001 |
| CAG | −0.18 | −0.43 to 0.07 | 0.160 |
| Age | −0.13 | −0.22 to −0.05 | 0.003 |
| Sex (female) | 1.71 | 0.27 to 3.15 | 0.020 |
| Antipsychotic | 2.75 | 1.42 to 4.08 | <0.001 |
Numbers in bold indicate p values <0.05.
*Random effect with mean 45.52 and SD=2.76.
†Random effect with mean −0.43 and SD=0.46.
‡Total behavioural disturbances excluding psychotic symptoms.
§Random effect with mean 25.46 and SD=9.67.
¶Random effect with mean 0.00 and SD=0.00.
CAG, cytosine–adenine–guanine.