Table 1

Quantitative sensory findings in CIPN*

Type of chemotherapy	Mechanical sensibility	VDT	CDT/WDT
Taxanes	Reduced touch detection^s42,s50	Increased VDT^{s43–s45,s48,s50}	No change/mildly elevated WDT or CDT^{s42,s46–s48,s50}
Cisplatin	Reduced touch detection or no change in some series^17,s112	Increased VDT^17,s53–s55	No change/mildly elevated at high dose^17,s112
Oxaliplatin	Reduced touch detection in lower limbs or no change in some series^s112–s114	Increased VDT^s55,s56,s110	Inconsistent findings (no change, impaired in minority or increased CDT and WDT)^{s50,s57,s112,s113}
Vincristine	Reduced touch detection^s58,s84	Increased VDT^s111	Increased WDT^s58
Bortezomib	Reduced touch detection^s59,s60	–	Increased WDT^s59

*Cited studies in superscript numbers.
CDT, cold detection threshold;CIPN, chemotherapy-induced peripheral neurotoxicity; VDT, vibration detection threshold; WDT, warm detection threshold.