Family history of neuropsychiatric disorders and MND-FTD subclass
| Any neuropsychiatric in family history | Mood disorder | Neurotic disorder | Schizophrenia, schizotypal and delusional disorders | |||||
| OR | 95% CI | OR | 95% CI | OR | 95% CI | OR | 95% CI | |
| MND (ref) | – | – | – | – | – | – | – | – |
| MND-FTD | 5.077 | 1.263 to 20.403 | 7.571 | 1.555 to 46.867 | 13.750 | 1.705 to 110.861 | 6.111 | 0.504 to 74.061 |
| MNDbi | 3.136 | 1.094 to 8.989 | 1.606 | 0.304 to 8.488 | 5.000 | 0.668 to 37.418 | 5.000 | 0.667 to 37.418 |
| MNDci | 1.202 | 0.484 to 2.988 | 0.841 | 0.203 to 3.482 | 0.846 | 0.075 to 9.515 | 3.548 | 0.632 to 19.929 |
| MNDcbi | 1.270 | 0.328 to 4.906 | 1.860 | 0.349 to 9.910 | 5.789 | 0.768 to 43.623 | 2.750 | 0.238 to 31.781 |
Results in bold indicate a significant association.
MND, motor neuron disease; MNDbi, motor neuron disease with behavioural impairment; MNDcbi, motor neuron disease with cognitive and behavioural impairment; MNDci, motor neuron disease with cognitive impairment; MND-FTD, motor neuron disease–frontotemporal dementia.