Table 1

Summary of the effect of any VRF (Model 1) and of each individual VRF (Model 2) on the number of Dawson’s fingers and JCL

ParameterDawson’s fingersJCLU-S JCL
Exp(B)95% CI, Exp(B)P valueExp(B)95% CI, Exp(B)P valueExp(B)95% CI, Exp(B)P value
Model 1
 VRF (n=106)1.050.89 to 1.220.551.271.11 to 1.44<0.01**0.810.57 to 1.150.26
 Disease duration1.031.02 to 1.03<0.01**1.021.01 to 1.02<0.01**1.021.00 to 1.030.03*
Model 2
 Smoking* (n=80)1.291.10 to 1.51<0.01**1.381.21 to 1.57<0.01**1.140.79 to 1.640.47
 Hypertension (n=43)†0.860.70 to 1.1060.170.850.71 to 1.010.060.610.36 to 1.020.06
 Dyslipidaemia (n=25)‡0.970.77 to 1.230.801.301.10 to 1.56<0.01**0.850.48 to 1.530.59
 Diabetes (n=10)§0.660.41 to 1.070.090.340.20 to 0.58<0.01**0.350.09 to 1.460.15
 Disease duration1.041.03 to 1.04<0.01**1.021.02 to 1.03<0.01**1.021.00 to 1.040.03*
 Age0.970.96 to 98<0.01**0.980.97 to 0.99<0.01**0.990.97 to 1.020.63

  • **P<0.01.

  • *Cases were considered to be smokers if they had ever smoked >10 cigarettes a day for at least 6 months.

  • †Hypertension was diagnosed if blood pressure >149/90 mm Hg or on antihypertensive treatment.

  • ‡Hypercholesterolemia was diagnosed if total cholesterol >5.0 mmol (193 mg/dL) and/or hypertriglyceridaemia (ever) (triglycerides>1.8 mmmo/L (150 mg/dL) or on antidyslipidaemia treatment.

  • §Diabetes mellitus was diagnosed according to WHO definitions6 (diabetes symptoms plus: HbA1c ≥ 6.5% (48 mmol/mol) or a random venous plasma glucose concentration ≥11.1 mmol/L or a fasting plasma glucose concentration ≥7.0 mmol/L or 2-hour plasma glucose concentration ≥11.1 mmol/L 2 hours after 75 g anhydrous glucose in an oral glucose tolerance test) or on antidiabetic treatment.

  • JCL, juxtacortical lesions; VRF, vascular risk factor.