Table 5

Stimulation of the dorsal fornix or the mammillothalamic tract in rodent models

OutcomeSpeciesStimulation frequency (Hz)Dorsal fornixMammillothalamic tract
Thalamic theta oscillationsRat1Increase of theta power (Tsanov et al 2011c)No increase of theta power (Tsanov et al 2011c)
100No increase of theta power
(Tsanov et al 2011c)
No increase of theta power (Tsanov et al 2011c)
Thalamic synaptic plasticityRat1LTD of FP slope and amplitude (Tsanov et al 2011d)LTP of FP slope and amplitude (Tsanov et al 2011d)
100LTP of the FP slope, no effect on FP amplitude (Tsanov et al 2011d)LTP of FP slope and amplitude (Tsanov et al 2011d)
BiochemistryRat scopolamine IP (0.1 mg/kg)10c-Fos increase in infralimbic and prelimbic cortices (Hescham et al 2015b)
100
MemoryRat scopolamine IP (0.1 mg/kg)10No effect on object location task (Hescham et al 2015b)
100No effect on object location task (Hescham et al 2015b)
  • FP, field potential; IP, intraperitoneal; LTD, long-term depression; LTP, long-term potentiation.