Table 5

Group 1. Multivariate regression analysis showing factors associated with change in composite cognitive score

Predictor variableChange in total cognitive z-score
B coefficientP value
Constant−1.6890.781
Group (antidopaminergic takers vs non-antidopaminergic takers)−1.244<0.001
Age0.0460.071
Gender0.0830.493
CAG repeat length0.0940.430
DBS−0.0080.008
TFC−0.0390.586
Time since diagnosis0.0200.619
UHDRS total motor score−0.0030.813
Depression (PBA)−0.0120.659
Irritability (PBA)−0.0590.087
Apathy (PBA)0.0300.445
ISCED−0.1550.183
  • ISCED, The International Standard Classification of Education; CAG, cytosine-adenine-guanine.

  • DBS, disease burden score; PBS, problems behavioural assessment; TFC, total functional capacity; UHDRS, Unified Huntington Disease Rating Scale.