Demographics and clinical characteristics of patients with post-traumatic cluster headache
| Sex | Age of onset | Current age | Follow-up duration (years) | Type of CH | Other associated headache | Characteristics of attacks | Response to treatment | |||||||
| Laterality | Average duration (min) | Average frequency (per day) | Autonomic feature | Restlessness | Migrainous symptoms | Intractable to acute treatment | Intractable to preventive treatment | |||||||
| 1 | M | 15 | 34 | 10 | CCH* | – | Side variable | 50 | 3 | C, L, N, R, E, FS, P | Yes | N, V | No | No |
| 2 | M | 32 | 54 | 10 | CCH | Episodic migraine | L | 60 | 2 | C, L, N, R, E, FF, P | Yes | PT, PN, OSM, N | No | No |
| 3 | M | 18 | 38 | 10 | ECH | – | R | 120 | 3 | C, L, N, E, FS, P | Yes | PT, PN, N, V, OSM | No | No |
| 4 | F | 36 | 54 | 10 | CCH* | Episodic migraine | Side variable | 90 | 3 | N, E, P | Yes | PT, PN, N, V, OSM | No | Yes |
| 5 | M | 33 | 64 | 8 | CCH* | – | R | 90 | 6 | L, N, R, FS, FF, P, AF | Yes | PT, PN, OSM | No | Yes |
| 6 | M | 43 | 57 | 8 | CCH | Episodic migraine | L | 150 | 1 | L, R | Yes | PT, PN | No | No |
| 7 | M | 20 | 34 | 3 | CCH* | – | R | 40 | 5 | C, L, N, R, E, FS, P | Yes | – | No | No |
| 8 | M | 10 | 55 | 8 | PECH | – | R | 180 | 6 | C, L, N, R, FS, FF, P, AF | Yes | PT, PN | No | Yes |
| 9 | M | 22 | 38 | 8 | CCH | Chronic migraine | L | 50 | 5 | C, L, N, R, E, FS, FF, P | Yes | PT, PN, OSM | No | No |
| 10 | M | 26 | 52 | 8 | CCH* | – | R | 120 | 2 | C, L, N, FF, FS, P | Yes | OSM | Yes | Yes |
| 11 | F | 45 | 58 | 8 | CCH | Episodic migraine | L | 120 | 2 | FS, AF, P | Yes | PN, N, MS | No | Yes |
| 12 | F | 29 | 42 | 7 | CCH | – | L | 120 | 6 | C, L, N, R, E, P | Yes | N, OSM | No | Only 3 trials done |
| 13 | F | 11 | 23 | 5.5 | CCH | – | Side variable | 90 | 2 | C, L, R, E, P | Yes | PT, N | NA | NA |
| 14 | M | 54 | 57 | 5 | CCH | – | L | 150 | 1 | C, FF, FS | No | – | Yes | Yes |
| 15 | M | 48 | 59 | 5 | CCH | L | 45 | 2 | C, L, N, R, E, FS, P | Yes | PT, PN | No | Yes | |
| 16 | F | 47 | 61 | 4 | CCH | Chronic migraine | Side variable | 120 | 3 | L, N, FF, FS | Yes | – | No | Yes |
| 17 | M | 24 | 33 | 2.5 | CCH | Chronic migraine | L | 30 | 5 | C, L, N, R, E, FS, FF, P | Yes | PT, PN, N, V, OSM | No | Only 3 trials done |
| 18 | M | 45 | 52 | 5 | PECH | Episodic migraine | L | 210 | 3 | C, R, E, FS | Yes | N | No | No |
| 19 | M | 56 | 62 | 2 | CCH | Chronic migraine | L | 180 | 2 | NA | Yes | PT, PN | No | Yes |
| 20 | F | 51 | 64 | 8 | ECH | – | L | 30 | 3 | C, L, N, R, FS, P | Yes | PT | No | Only 3 trials done |
| 21 | M | 28 | 45 | 1 | CCH* | – | L | 120 | 4 | C, L, N, R, E, FS, FF, P | Yes | PT | No | No |
| 22 | M | 38 | 48 | 4.5 | CCH | – | R | 30 | 6 | C, L, N, R, E, FS, FF, P | Yes | – | No | Yes |
| 23 | M | 26 | 39 | 10.5 | CCH | – | L | 20 | 8 | C, L, N, R, FS, FF | Yes | PT, PN | No | Yes |
| 24 | M | 24 | 36 | 6.5 | CCH | Chronic migraine | R | 60 | 2 | C, L, N, P, AF | No | PT, PN, N | No | No |
| 25 | M | 33 | 48 | 7 | CCH | – | L | 60 | 4 | C, L, N, R, E, P | Yes | PN, N | No | Only 3 trials done |
| 26 | F | 17 | 52 | 5 | ECH | Episodic migraine | L | 45 | 3 | L, N, R | Yes | PT, PN, N, OSM | No | Only 3 trials done |
Autonomic feature: AF, aural fullness; C, conjunctival injection; E, eyelid oedema; FF, facial flushing; FS, facial sweating; L, lacrimation; N, nasal congestion; P, ptosis; R, rhinorrhoea.
Migrainous symptoms: MS, motion sensitivity; N, nausea; OSM, osmophobia; PN, phonophobia; PT, photophobia; V, vomiting.
*Secondary chronic cluster headache phenotype (initially episodic and subsequently transformed to chronic variant).
CCH, chronic cluster headache; CH, cluster headache; ECH, episodic cluster headache; F, female; L, left; M, male; NA, not available; PECH, probable episodic cluster headache; R, right.