Table 2

Demographic and clinical characteristics of TPH2 GG homozygotes and T carriers

GG (n=37)TT/TG (n=32)P value
Age, mean (SD)47.1 (11.6)40.5 (12.1) 0.03
Female, n (%)31 (84)23 (72)0.26
Disease duration, mean (SD)5.4 (7.3)7.4 (8.6)0.32
HAM-A, mean (SD)13.1 (7.4)14.2 (8.5)0.58
HAM-D, mean (SD)9.4 (5.9)10.8 (7.2)0.37
CTQ, mean (SD)38.4 (18.6)43.6 (14.5)0.21
Depression Dx (SCID), n (%)3 (8)4 (13)0.70
  • CTQ, Childhood Trauma Questionnaire; Dx, diagnosis; HAM-A, Hamilton Anxiety Rating Scale; HAM-D, Hamilton Rating Scale for Depression; SCID, Structured Clinical Interview for DSM-IV-TR, Patient Edition.