Table 3

Cox regression analyses for recurrent ICH events

UnivariableMultivariable
HR95% CIP valueHR95% CIP value
ICH location, lobar (vs non-lobar)5.402.60 to 11.24<0.00018.963.36 to 23.87<0.0001
Age, per year increase1.031.00 to 1.060.0391.020.98 to 1.060.349
Previous cerebral ischaemic event2.321.25 to 4.340.0082.861.37 to 5.960.005
Previous ICH5.002.22 to 11.24<0.00014.861.41 to 16.670.012
APOE ε21.840.93 to 3.650.0801.370.65 to 2.900.415
Antiplatelet use prior to ICH2.241.24 to 4.040.0082.221.09 to 4.500.028
Van Swieten Score, per point increase1.291.07 to 1.550.0081.220.97 to 1.530.084
ICH volume<30 mLReference groupReference group
30–60 mL2.140.95 to 4.820.0681.060.40 to 2.810.911
>60 mL0.780.11 to 5.680.804
  • Multivariable results for ICH volume > 60mL not shown as only one event in this group (HR<0.0001).

  • APOE, Apolipoprotein E; CI, confidence interval; HR, hazard ratio; ICH, intracerebral haemorrhage.