Baseline characteristics of participants who developed all-cause dementia
| SCANS | RUN DMC | |||||
| Dementia (n = 24) | No dementia (n = 97) | P | Dementia (n = 38) | No dementia (n = 314) | P | |
| Age | 72.1 (10.5) | 69.5 (9.5) | 0.189 | 78.5 (4.5) | 68.0 (7.8) | <0.001 |
| Sex, female (%) | 5 (20.8) | 38 (39.2) | 0.149 | 12 (31.6) | 130 (41.4) | 0.322 |
| Education | 0.043 | 0.002 | ||||
| Low (%) | 12 (52.2) | 44 (45.4) | 9 (23.7) | 25 (8.0) | ||
| Medium (%) | 11 (47.8) | 32 (33.0) | 23 (60.5) | 175 (55.7) | ||
| High (%) | 0 (0.0) | 21 (21.6) | 6 (15.8) | 114 (36.3) | ||
| BMI, kg/m2 | 25.6 (5.7) | 27.3 (4.6) | 0.032 | 26.6 (5.9) | 28.0 (4.3) | 0.218 |
| Hypertension (%) | 23 (95.8) | 89 (91.8) | 0.804 | 30 (78.9) | 253 (80.6) | 0.982 |
| Diabetes (%) | 7 (29.2) | 15 (15.5) | 0.207 | 8 (22.2) | 44 (14.6) | 0.342 |
| Hypercholesterolaemia (%) | 23 (95.8) | 81 (83.5) | 0.219 | 27 (75.0) | 148 (49.2) | 0.006 |
| Smoking | 0.777 | 0.331 | ||||
| Never (%) | 9 (37.5) | 39 (40.2) | 8 (21.1) | 95 (30.3) | ||
| Ex (%) | 9 (37.5) | 40 (41.2) | 23 (60.5) | 182 (58.0) | ||
| Current (%) | 6 (25.0) | 18 (18.6) | 7 (18.4) | 37 (11.8) | ||
| Apathy | 3.6 (1.7) | 2.8 (1.7) | 0.047 | 35.6 (11.6) | 26.6 (7.0) | <0.001 |
| Depression | 6.4 (6.0) | 5.5 (5.1) | 0.527 | 13.8 (5.8) | 14.4 (4.0) | 0.326 |
| MMSE | 24.9 (3.8) | 28.2 (1.8) | <0.001 | 24.3 (3.5) | 28.5 (1.4) | <0.001 |
| PS index | −2.0 (0.4) | −0.8 (0.8) | <0.001 | −1.9 (0.5) | −1.1 (0.7) | <0.001 |
| IADL | 6.4 (2.0) | 7.7 (0.7) | <0.001 | 6.2 (2.1) | 7.9 (0.5) | <0.001 |
BMI, body mass index; IADL, Instrumental Activities of Daily Living; MMSE, Mini Mental State Examination; PS, processing speed; RUN DMC, Radboud University Nijmegen Diffusion Tensor and Magnetic Resonance Cohort; SCANS, St. George's Cognition and Neuroimaging in Stroke.