Table 4

Quantitative measures of behaviour change in bvFTD and FTD-ALS

bvFTD
(n=22)
FTD-ALS
(n=17)
Mann-Whitney
Median (range)Median (range)zP value
NPI
 Delusions0 (0–8)0 (0–10)−0.00.97
 Hallucinations0 (0–8)0 (0–4)−0.70.48
 Agitation3 (0–8)0 (0–3)−2.70.01*
 Depression0 (0–6)0 (0–6)−1.90.06
 Anxiety0 (0–8)1 (0–4)−0.20.87
 Elation0 (0–8)0 (0–6)−1.90.06
 Apathy8 (0–12)4 (0–8)−2.00.05
 Disinhibition3 (0–8)0 (0–6)*−2.30.02*
 Irritability1 (0–12)0 (0–2)−2.00.05
 Aberrant motor behaviour1 (0–12)0 (0–12)−0.70.47
 Sleep0 (0–12)0 (0–12)*−0.70.91
 Appetite8 (0–12)6 (0–12)−1.20.25
FrSBe
 Apathy change36.5 (5–52)29 (7–49)−0.730.46
 Disinhibition change17.5 (3–57)10 (−4–32)−2.190.03*
 Executive change34 (3–64)18 (8–47)−2.130.03*
  • *n=16; *p<0.05.

  • ALS, amyotrophic lateral sclerosis; bvFTD, behavioural variant FTD; FrSBe, Frontal Systems Behaviour Scale; FTD, frontotemporal dementia; NPI, neuropsychiatric inventory.