Table 2

Baseline characteristics of the participants with available middle-age CAIDE score and educational-occupational score*

Those who had CAIDE score and participated in cognition interview (n=2359)Those who had CAIDE score and did not participate in the cognition interview (n=559)P value for the difference between groups*Those who had educational-occupational score and participated in cognition interview (n=3982)Those who had educational-occupational score and did not participate in the cognition interview (n=1315)P value for the difference between groups*
Age (years, mean, SD)49.1 (5.9)47.8 (6.1)<0.000145.5 (6.5)43.8 (6.9)<0.0001
Education (years, mean, SD)8.0 (2.9)7.4 (2.6)<0.00017.9 (2.9)7.2 (2.4)<0.0001
Blood pressure
 Normal (n, %)1748 (74.1)413 (73.9)3006 (76.2)1015 (78.6)
 Slightly elevated or elevated (n, %)611 (25.9)146 (26.1)0.92937 (23.8)276 (21.4)0.08
 BMI (kg/m2, mean, SD)24.5 (3.0)24.3 (3.1)0.2124.5 (3.0)24.3 (3.2)0.09
Cholesterol level
 Normal (n, %)1626 (68.9)403 (72.1)1655 (68.7)409 (72.3)
 Elevated (n, %)733 (31.1)156 (27.9)0.14755 (31.3)157 (27.7)0.10
Physical activity
 Active (n, %)604 (25.6)147 (26.2)977 (24.6)290 (22.2)
 Inactive (n, %)1755 (74.4)412 (73.7)0.742988 (75.4)1019 (77.8)0.07
Diabetes
 No diabetes (n, %)2323 (98.6)550 (98.4)3924 (99.0)1285 (98.5)
 Diabetes (n, %)32 (1.4)9 (1.6)0.6543 (1.1)19 (1.5)0.28
Smoking status
 Never smoker (n, %)1234 (52.4)304 (54.5)2103 (52.9)666 (50.8)
 Occasional smoker (n, %)68 (2.9)18 (3.2)120 (3.0)33 (2.5)
 Former smoker (n, %)604 (25.6)120 (21.5)954 (24.0)264 (20.2)
 Current smoker (n, %)450 (19.1)116 (20.8)0.23798 (20.1)347 (26.5)<0.001
Work status
 Working/studying (n, %)2106 (89.4)474 (85.1)3420 (85.9)1079 (82.0)
 Home maker (n, %)160 (6.8)50 (9.0)358 (9.0)150 (11.4)
 Not working (n, %)91 (3.9)33 (5.9)0.02204 (5.1)86 (6.5)<0.01
Nature of work
 Very monotonous (n, %)44 (1.9)14 (2.5)80 (2.0)41 (10.3)
 Somewhat monotonous/somewhat variable (n, %)1625 (69.4)422 (76.6)2800 (70.4)974 (24.5)
 Very variable (n, %)672 (28.7)115 (20.9)<0.011097 (27.6)298 (7.5)<0.001
Work environment
 Outdoors/outdoors and indoors (n,
 %)
741 (31.4)167 (29.9)1372 (34.5)455 (34.6)
 Indoors (n, %)1616 (68.6)391 (70.1)0.492610 (65.5)860 (65.4)0.92
Physicality of work
 Heavy manual labour (n, %)212 (9.0)52 (9.4)431 (10.8)155 (11.8)
 Manual labour: standing and walking+lifting and carrying (n, %)808 (34.3)246 (44.2)1475 (37.0)599 (45.6)
 Manual labour: standing and walking
 (n, %)
427 (18.1)99 (17.8)695 (17.5)227 (17.3)
 Mainly sitting, very little physical activity required (n, %)909 (38.6)159 (28.6)<0.0011381 (34.7)334 (25.4)<0.001
CAIDE score6.7 (2.8)6.5 (2.7)0.096.7 (2.8)6.5 (2.7)0.10
Educational-occupational score17.8 (3.2)17.6 (3.0)0.1017.5 (3.3)17.1 (3.0)<0.01
  • *Statistical difference tested with t-test for continuous values and with χ2 test for categorical values.

  • †The percentage of data used from 1981 for CAIDE score (the rest of the data comes from 1990 for cholesterol values and from 1975 for the other values): cholesterol 55.8%, blood pressure 90.0%, body mass index (BMI) 96.6%, physical activity 96.4%, education 96.9% and age 55.8%. The percentage of data used from 1981 for educational-occupational score (the rest of the data comes from 1975): education 96.9%, work status 96.5%, nature of work 96.4%, work environment 96.6%, physicality of work 96.2% and age 97.0%.