Table 2

Observed transitions and 12-month transition probabilities

SubsampleForward transitionsBackward transitionsState maintenance over successive study visitsTransitions between states and death
NCI to MCIMCI to DEMNCI from MCIMCI from DEMNCIMCIDEMNCIMCIDEM
NCI at baseline2014 (4.7%)483 (15.1%)542 (14.6%)47 (4.5%)40‚ÄČ197 (93.4%)1973 (63.8%)916 (73.6%)783 (1.3%)275 (6.5%)347 (21.5%)
MCI at baseline341 (15.3%)2191 (16.9%)925 (8.0%)133 (2.6%)1535 (81.0%)7684 (73.4%)3738 (84.1%)58 (2.0%)280 (1.6%)801 (13.2%)
  • Values represent the total number of observed transitions and are accompanied by 12-month transition probabilities in parentheses. Forward transitions represent worsening cognitive impairment; backward transitions represent improving cognitive functioning.

  • DEM, dementia; MCI, mild cognitive impairment; NCI, not cognitively impaired.