Table 2

Characteristics of patients with different infarct loads in the territory of the diseased intracranial artery of interest*

Characteristics (n=180)Infarct loads in the relevant territoryP value †P value‡
None (n=26)Acute infarct(s) only or chronic infarct(s) only (n=125)Coexisting acute and chronic infarcts (n=29)
Age, years55 (51–62)61 (55–69)62 (57–69)0.0040.255
Male19 (73.1)76 (60.8)19 (65.5)0.4800.790
Current smoker15 (57.7)52 (41.6)17 (58.6)0.1210.159
History of dyslipidaemia18 (69.2)100 (80.0)25 (86.2)0.2870.325
History of hypertension13 (50.0)84 (67.2)26 (89.7)0.0060.007
History of diabetes4 (15.4)46 (36.8)14 (48.3)0.0340.118
Systolic blood pressure, mm Hg152 (133–169)150 (136–165)159 (138–172)0.5270.259
Diastolic blood pressure, mm Hg85 (76–93)80 (70–90)83 (71–94)0.3170.556
Laboratory test results
 Glycosylated haemoglobin, %6.0 (5.3–6.4)6.2 (5.7–7.5)6.4 (5.9–7.5)0.0300.353
 Fasting blood glucose, mmol/L5.1 (4.9–5.9)5.8 (5.1–7.3)6.4 (5.2–7.4)0.0310.293
 Low-density lipoprotein, mmol/L3.3 (2.4–4.6)3.4 (2.7–4.1)3.3 (2.8–3.9)0.8590.582
 High-density lipoprotein, mmol/L1.3 (1.0–1.5)1.1 (0.9–1.3)1.2 (0.9–1.5)0.0910.277
 Triglycerides, mmol/L1.3 (0.9–1.6)1.5 (1.2–2.0)1.6 (1.2–2.1)0.1430.890
Location of the qualifying ICAD lesions0.2860.447
 MCA-M120 (76.9)91 (72.8)21 (72.4)
 Terminal ICA1 (3.8)20 (16.0)5 (17.2)
 Across terminal ICA and proximal MCA2 (7.7)2 (1.6)2 (6.9)
 VA-V4 or BA3 (11.5)12 (9.6)1 (3.4)
Plaque types0.0320.007
 Smooth8 (30.8)38 (30.4)5 (17.2)
 Irregular15 (57.7)72 (57.6)14 (48.3)
 Ulcerative3 (11.5)15 (12.0)10 (34.5)
Arterial luminal stenosis, %78 (72–83)75 (71–85)75 (70–82)0.7810.519
  • *Values are medians (IQR) or numbers (%); Kruskal-Wallis tests or Wilcoxon rank-sum tests were used for comparison of continuous variables and χ2 tests for categorical variables.

  • †P values for comparisons among the three groups.

  • ‡P values for comparisons between patients with coexisting acute and chronic infarcts in the relevant territory and other patients.

  • ICAD, intracranial atherosclerotic disease; MCA-M1, M1 middle cerebral artery; ICA, internal carotid artery; VA-V4, V4 vertebral artery; BA, basilar artery.