Differentially expressed miRNAs identified by EdgeR, after correction for multiple comparisons, for each pairwise comparison between clinical status: Control (n=43), presymptomatic (n=45) and patient (n=22)
miRNA | Log-fold change | P value | Adjusted p value |
Control vs presymptomatic | |||
miR-34a-5p | −1.433 | 5.251e-16 | 3.093e-13 |
Control vs patient | |||
miR-34a-5p | −1.239 | 1.650e-8 | 9.720e-6 |
miR-345-5p | −0.540 | 1.131e-5 | 3.330e-3 |
miR-200c-3p | 0.333 | 3.109e-5 | 6.104e-3 |
miR-10a-3p | 0.697 | 7.141e-5 | 1.051e-2 |
Presymptomatic vs patient | |||
miR-345-5p | −0.528 | 3.610e-5 | 2.126e-2 |
miRNA, microRNA.