Table 3

Risk factors for presence of ICAS in the two cohorts

Risk factorsOXVASC (n=1287)CUHK-SR (n=691)
Crude
OR (95% CI)
P valueAge-adjusted
OR (95% CI)
P valueMultivariable-adjusted
OR (95% CI)
P valueCrude
OR (95% CI)
P valueAge-adjusted
OR (95% CI)
P valueMultivariable-adjusted
OR (95% CI)
P value
Age
(every 10 years increment)
1.65 (1.46 to 1.87)<0.0011.62 (1.42 to 1.84)<0.0011.33 (1.17 to 1.52)<0.0011.23 (1.08 to 1.41)0.003
Male sex1.17 (0.89 to 1.53)0.2761.40 (1.05 to 1.86)0.0221.36 (1.01 to 1.84)0.0420.87 (0.64 to 1.19)0.3750.91 (0.66 to 1.25)0.5550.96 (0.70 to 1.33)0.810
Ever-smoker1.01 (0.77 to 1.33)0.9431.12 (0.84 to 1.48)0.4450.98 (0.73 to 1.32)0.9101.00 (0.73 to 1.36)0.9941.01 (0.74 to 1.38)0.9671.02 (0.74 to 1.40)0.894
History of hypertension2.23 (1.66 to 2.99)<0.0011.67 (1.23 to 2.27)0.0011.51 (1.09 to 2.08)0.0121.92 (1.38 to 2.66)<0.0011.64 (1.17 to 2.31)0.0041.43 (1.00 to 2.03)0.047
History of diabetes1.79 (1.24 to 2.57)0.0021.74 (1.19 to 2.53)0.0041.46 (0.98 to 2.16)0.0572.02 (1.44 to 2.85)<0.0011.86 (1.32 to 2.64)<0.0011.67 (1.17 to 2.38)0.005
History of dyslipidaemia1.65 (1.25 to 2.18)<0.0011.42 (1.06 to 1.89)0.0171.17 (0.86 to 1.58)0.3191.64 (1.21 to 2.23)0.0011.50 (1.10 to 2.05)0.0101.34 (0.98 to 1.85)0.069
  • CUHK-SR, the Chinese University of Hong Kong Stroke Registry; ; ICAS, intracranial atherosclerotic stenosis; OXVASC, Oxford Vascular Study.