The impact of UK COVID-19 lockdown on IIH disease activity
| Change in IIH disease status (prelockdown to postlockdown) | Prelockdown mean (SD) | Postlockdown mean (SD) | Change mean (SD) % | |
| Remission to active (n=4) | ||||
| Weight | 109.2 (12.0) | 113.8 (15.2) | +4.7 (10.0) | +4.3% |
| BMI | 42.1 (8.0) | 42.9 (10) | +0.8 (7.5) | +2.4% |
| Papilloedema | 102 (6) | 128 (16) | +36 (22) | +37% |
| Active to Active (n=29) | ||||
| Weight | 99.6 (31.3) | 103.5 (30.9) | +1.96 (6.3) | +2.1% |
| BMI | 37.1 (9.6) | 38.0 (9.5) | +0.21 (3.4) | +1% |
| Papilloedema | 130 (39) | 137 (70) | +5 (72) | +6% |
| Remission to Remission (n=30) | ||||
| Weight | 103.7 (21.1) | 106.5 (21.3) | +4.2 (22.2) | −0.5% |
| BMI | 39.3 (8.6) | 39.1 (8.3) | +0.9 (7.8) | −2.3% |
| Papilloedema | 89 (23) | 88 (21) | −1 (12) | 0% |
| Active to Remission (n=15) | ||||
| Weight | 110.8 (24.9) | 110.6 (26.3) | +0.7 (6.2) | +0.5% |
| BMI | 41.5 (10.4) | 40.7 (9.8) | −0.3 (2.6) | −0.6% |
| Papilloedema | 107 (44) | 87 (18) | −15 (23) | −11% |
BMI (kg/m2) indicates body mass index. Papilloedema measured by RNFL thickness (µm). Weight is measured in kg. Remission indicates the absence of papilloedema. Active indicates the presence of papilloedema.
IIH, intracranial hypertension; RNFL, retinal nerve fibre layer.