Table 2

Disagreement between the different selection paradigms

DisagreementNP value*
DEFUSE-3-PIM(+)/DAWN-CCM(−)40<0.001
DEFUSE-3-PIM(−)/DAWN-CCM(+)12
DEFUSE-3-PIM(+)/mCAM(−)280.14
DEFUSE-3-PIM(−)/mCAM(+)17
DEFUSE-3-PIM(+)/eCAM(−)260.22
DEFUSE-3-PIM(−)/eCAM(+)17
DEFUSE-3-PIM(+)/sCAM(−)200.74
DEFUSE-3-PIM(−)/sCAM(+)17
DAWN-CCM(+)/mCAM(−)200.03
DAWN-CCM(−)/mCAM(+)37
DAWN-CCM(+)/eCAM(−)190.02
DAWN-CCM(−)/eCAM(+)38
DAWN-CCM(+)/sCAM(−)150.001
DAWN-CCM(−)/sCAM(+)40
mCAM(+)/eCAM(−)40.75
mCAM(−)/eCAM(+)6
mCAM(+)/sCAM(−)00.008
mCAM(−)/sCAM(+)8
eCAM(+)/sCAM(−)00.03
eCAM(−)sCAM(+)6
  • (+) denotes selection by the specified methodology, while (–) denotes exclusion for ET by that methodology.

  • *McNemar test for discordant pairs.

  • aCAM, age-adjusted clinical ASPECTS mismatch; DAWN-CCM, DAWN clinical core mismatch; DEFUSE-3-PIM, DEFUSE 3 perfusion imaging mismatch; eCAM, eloquence-adjusted clinical ASPECTS mismatch.