Clinical/laboratory factor | Score |
Ab against intracellular antigen (or high clinical relevance surface antibody) | 1 |
Movement disorder and/or stiff person syndrome | 1 |
Cancer and/or smoking history | 1 |
Inflammatory CSF (either high cell count, IgG index and/or positive OCBs) | 1 |
Serum hyponatraemia | 1 |
Chronic course (>3 months)† | −1 |
Total | Maximum=5 Minimum=−1 |
Modified from Abboud et al. 33
*Based on a study in patients tested for the original Mayo Clinic Paraneoplastic panel not the Autoimmune Encephalitis Panel.
†Although chronic course is rare in autoimmune encephalitis, patients with leucine-rich glioma inactivated-1, CASPR2 and IgLON5-antibodies can have a chronic course.
Ab, antibody; CSF, cerebrospinal fluid; OCBs, oligoclonal bands.