OR with 95% CI of developing relapsing-onset and progressive-onset MS among subjects with different smoking habits
| Smoking | Relapsing-onset MS | Progressive-onset MS | ||||
| ca/co* | aOR (95% CI)† | aOR (95% CI)‡ | Ca/co* | aOR (95% CI)† | aOR (95% CI)‡ | |
| Never smoking | 3412/6280 | 1.0 (reference) | 1.0 (reference) | 208/6280 | 1.0 (reference) | 1.0 (reference) |
| Ever smoking | 4108/5106 | 1.5 (1.4 to 1.6) | 1.6 (1.5 to 1.7) | 332/5106 | 1.7 (1.4 to 2.0) | 1.9 (1.6 to 2.3) |
| Current smoking | 2670/2984 | 1.7 (1.6 to 1.8) | 1.7 (1.6 to 1.8) | 190/2984 | 2.0 (1.7 to 2.5) | 2.3 (1.9 to 2.8) |
| Past smoking | 1438/2122 | 1.3 (1.2 to 1.5) | 1.4 (1.3 to 1.5) | 142/2122 | 1.3 (1.1 to 1.7) | 1.5 (1.2 to 1.9) |
*Number of exposed cases and controls.
†Adjusted for study, year of enrolment, age, sex, residential area and ancestry.
‡Adjusted for study, year of enrolment, age, sex, residential area, ancestry, obesity, alcohol consumption, sun exposure habits and snuff use. The analyses are based on 7520 relapsing-onset MS cases, 540 progressive-onset MS cases and 11 386 controls.
aOR, adjusted OR; MS, multiple sclerosis.