Table 1

Demographic characteristics for patients included in Motor and Cognitive Scale development cohorts, all of whom had a clinical diagnosis of sCJD

Motor Scale development cohortCognitive Scale development cohort
No. of patients (assessments)106 (144)155 (231)
Mean age (SD)67.0 (7.4)64.5 (8.6)
Gender M/F52/5493/62
Codon 129
MM (%)30 (28.0)28 (18.1)
MV (%)26 (24.5)45 (29.0)
VV (%)29 (27.3)54 (34.8)
Unknown (%)21 (19.8)28 (18.1)
Mean MRC Scale score at assessment/20 (range, SD)8.6 (20–0, 5.2)11.6 (20–0, 4.2)
  • MM, MV, VV, codon 129 genotypes at PRNP ; MRC, Medical Research Council; sCJD, sporadic Creutzfeldt-Jakob disease.