Table 3

OCT results in patients who were AQP4-IgG seropositive stratified by history of on (Spectralis devices only)

AQP4-ONAQP4-NONMOG-ONMOG-NONAQP4-ON vs AQP4-NONAQP4-ON vs HCAQP-NON vs HCAQP4-ON vs MOG-ONAQP4-NON vs MOG-NON
BSEPBSEPBSEPBSEPBSEP
Number of eyes232854312
pRNFL in µm (mean±SD)72.84±24.4796.09±12.9968.03±22.9595.33±7.32−25.183.93<0.001−29.563.57<0.001−9.295.150.072.636.120.6676.035.440.275
GCIP in
µm (mean±SD)
62.94±12.7377.11±7.5663.45±11.9675.88±6.01−14.742.06<0.001−19.601.49<0.001−0.501.480.735−4.003.200.2153.223.360.344
OPL in
µm (mean±SD)
25.06±2.0124.71±1.7925.28±2.0824.45±1.550.260.380.4980.340.260.1840.090.380.8040.340.510.509−0.120.960.899
ONL in
µm (mean±SD)
62.53±7.4563.14±6.6266.09±8.0859.76±4.58−0.191.490.901−0.180.920.847−0.821.400.560−2.842.120.1832.763.580.446
OPNL in
µm (mean±SD)
87.58±7.6787.85±6.7884.21±5.6891.37±8.690.001.530.8790.270.950.7750.371.420.794−2.512.210.2592.673.510.450
PR in
µm (mean±SD)
80.89±2.9379.80±2.9482.01±3.4579.62±3.580.750.570.187−0.190.360.595−1.080.590.071−0.580.770.4541.361.440.348
  • AQP4, aquaporin-4 ; B, estimate; GCIP, ganglion cell and inner plexiform layer; HC, healthy control; MOG, myelin-oligodendrocyte-glycoprotein; NON, non-optic neuritis; ON, optic neuritis; ONL, outer nuclear layer; OPL, outer plexiform layer; OPNL, outer plexiform and nuclear layer; PR, photoreceptor layer; pRNFL, peripapillary retinal nerve fibre layer.