Table 5

Determinants of mortality (n=216)

OR95% CIP valueOR95% CIP value
Age (years)
 ≥602.411.25 to 4.670.0093.541.46 to 8.550.005
 Male0.750.42 to 1.340.334
 Caucasian0.640.30 to 1.370.253
 Others1.300.57 to 2.980.534
 Smoking1.920.73 to 5.070.186
 Atrial fibrillation0.800.34 to 1.850.599
 Prior anticoagulation0.640.17 to 2.430.509
 Coronary artery disease0.810.37 to 1.750.592
 Congestive heart failure1.010.47 to 2.200.975
 Diabetes mellitus2.461.38 to 4.370.0022.681.25 to 5.740.012
 Hypertension1.190.58 to 2.440.637
 Hyperlipidaemia0.930.52 to 1.680.815
 Previous stroke0.970.49 to 1.950.938
 Chronic kidney disease1.110.51 to 2.380.794
Admission NIHSS (one unit)1.091.05 to 1.13<0.0011.061.02 to 1.120.009
Large vessel occlusion3.101.68 to 5.70<0.0013.231.40 to 7.460.006
Stroke aetiology
 CS/ESUS0.860.37 to 2.000.721
 Large-artery atherosclerosis1.090.36 to 3.320.875
 Small-vessel occlusion0.290.06 to 1.440.130
 NLR (one unit)1.081.01 to 1.150.0201.071.02 to 1.130.009
 D dimer (×100 ng/mL)1.011.00 to 1.020.129
 Absolute lymphocyte (1000/µL)0.970.90 to 1.040.335
 Platelets1.001.00 to 1.000.547
IV tPA0.530.23 to 1.230.139
Thrombectomy0.870.42 to 1.810.712
sICH3.561.25 to 10.160.0176.411.74 to 23.670.005
  • Univariable and multivariable mixed effects binary logistic regression analyses were done to test for the impact of several determinants on mortality. Variables that had a p<0.1 were included in the final multivariable model.

  • *The results after multiple imputation using chained equations to handle missing data.

  • CS/ESUS, cryptogenic stroke/embolic stroke of undetermined source; NIHSS, National Institutes of Health Stroke Scale; NLR, neutrophil–lymphocyte ratio; sICH, symptomatic intracranial haemorrhage; IV tPA, intravenous tissue plasminogen activator.