Table 2

Weighted Cox regression analyses of time from onset to irreversibly reaching disability milestones

EndpointEvents menCensored menEvents womenCensored womenHR*, unweightedHR*, weighted95% CICox p value
EDSS 3†1854988390025681.3001.2271.138 to 1.323<0.001
EDSS 47742068132248461.4461.3641.240 to 1.502<0.001
EDSS 6443239970154671.6271.5291.342 to 1.743<0.001
Pyramidal FS score 26192223104151271.4301.3371.209 to 1.479<0.001
Cerebellar FS score 2195264725459141.8721.7961.483 to 2.174<0.0001
  • *HR with women as reference.

  • ‚ĆProportionality not met.

  • EDSS, Expanded Disability Status Scale; FS, Functional System.