Table 3

Weighted Cox regression analyses of time from birth to irreversibly reaching disability milestones

EndpointEvents menCensored menEvents womenCensored womenHR*, unweightedHR*, weighted95% CICox p value
EDSS 3†1854988390025681.1521.1751.090 to 1.266<0.01
EDSS 47742068132248461.2741.3101.193 to 1.440<0.001
EDSS 6443239970154671.4401.4881.311 to 1.690<0.001
Pyramidal FS score 26192223104151271.2681.2951.173 to 1.429<0.001
Cerebellar FS score 2195264725459141.5201.5861.322 to 1.902<0.0001
  • *HR with women as reference.

  • ‚ĆProportionality not met.

  • EDSS, Expanded Disability Status Scale; FS, Functional System.