(A) aSAH admissions overall and monthly volumes before and during the COVID-19 pandemic. (B) SAH admissions by severity: overall and monthly volumes before and during the COVID-19 pandemic
(A) | |||||||||
N | Overall volume | Monthly volume* | |||||||
Before COVID-19† | During COVID-19‡ | Change | P value | N | Before COVID-19 | During COVID-19 | P value | ||
% (95% CI) | Adjusted mean (SE) | ||||||||
Overall | 165 | 6912 | 6471 | −6.4 (−7.0 to −5.8) | 0.0001 | 172 | 3.84 (0.75) | 3.62 (0.74) | 0.03 |
Hospital aSAH volume§ | |||||||||
Low | 56 | 422 | 471 | 11.6 (8.9 to 15.0) | 0.101 | 57 | 0.56 (0.09) | 0.64 (0.11) | 0.142 |
Int. | 53 | 1460 | 1472 | 0.82 (0.47 to 1.4) | 0.825 | 56 | 2.28 (0.12) | 2.28 (0.15) | 0.977 |
High | 56 | 5030 | 4528 | −10.0 (−10.8 to −9.2) | <0.0001 | 59 | 8.14 (1.41) | 7.42 (1.39) | 0.008 |
Hospital aSAH volume stratified by hospital COVID-19 volume¶ | |||||||||
Low | 49 | 1788 | 1833 | 2.5 (1.9 to 3.4) | 0.455 | 52 | 2.94 (1.02) | 3.0 (1.03) | 0.657 |
Int. | 46 | 1456 | 1368 | −6.0 (−7.4 to −4.9) | 0.098 | 46 | 2.19 (0.73) | 2.03 (0.68) | 0.19 |
High | 47 | 2275 | 2074 | −8.8 (−10.1 to −7.7) | 0.002 | 49 | 3.77 (1.18) | 3.40 (1.15) | 0.137 |
(B) | |||||||||
N | Overall volume | Monthly volume* | |||||||
Before COVID-19† | During COVID-19‡ | Change | P value | N | Before COVID-19 | During COVID-19 | P value | ||
% (95% CI) | Adjusted mean (SE) | ||||||||
Mild | 125 | 2698 | 2562 | −5.0 (−5.9 to −4.3) | 0.061 | 125 | 1.92 (0.37) | 1.83 (0.36) | 0.205 |
Mod. | 125 | 981 | 900 | −8.3 (−10.2 to −6.7) | 0.062 | 125 | 0.60 (0.09) | 0.55 (0.09) | 0.204 |
Severe | 125 | 1508 | 1490 | −1.2 (−1.9 to −0.75) | 0.742 | 125 | 0.87 (0.16) | 0.86 (0.17) | 0.78 |
Table 1b: Mild, moderate and severe cases were defined as Hunt-Hess grades 1–2, 3 and 4–5, respectively. 125 hospitals submitted complete data 12-month prepandemic and pandemic data on grades.
*The monthly volume analysis is adjusted for the date of peak COVID-19 volume for each country, the start date of the second wave and the continent.
†Number of admissions during 12 months before COVID-19 pandemic.
‡Number of admissions during 12 months of COVID-19 pandemic;.
§P value: low versus int. ≤0.0001; low versus high=N/A; int. versus high=N/A.
¶P value: low versus int.=N/A, low versus high=N/A, int. versus high=0.002.
aSAH, aneurysmal subarachnoid haemorrhage; int., intermediate; mod., moderate; N/A, not applicable; n, number of hospitals; SAH, subarachnoid haemorrhage.