Group | FPHT | LEV | P value |
n | 80 | 93 | |
Age, year | 65±19 | 67±16 | 0.51 |
Male sex, (%) | 57 (71.3) | 60 (64.5) | 0.32 |
Height, cm | 163.0±9.1 | 161.5±9.7 | 0.32 |
Body weight, kg | 60.3±13.1 | 57.9±12.5 | 0.22 |
Previous history of liver disease | 3 (3.7) | 3 (3.2) | 0.87 |
Serum creatinine level on admission, mg/dL | 0.87 (0.7, 1.1) | 0.86 (0.6, 1.1) | 0.48 |
Type of status epilepticus | 0.48 | ||
Tonic clonic seizure | 57 (71.3) | 72 (77.4) | |
Tonic seizure | 0 (0) | 1 (1.1) | |
Repeated partial seizures | 10 (12.5) | 10 (10.8) | |
Absence of seizures | 0 (0) | 1 (1.1) | |
Complex partial seizure | 13 (16.3) | 9 (9.7) | |
Cause of status epilepticus | 0.37 | ||
Idiopathic seizure | 19 (23.8) | 15 (16.1) | |
Acute stroke | 6 (7.5) | 12 (12.9) | |
Old stroke | 22 (27.5) | 31 (33.3) | |
Acute trauma | 2 (2.5) | 2 (2.2) | |
Old trauma | 5 (6.3) | 1 (1.1) | |
Brain neoplasm | 11 (13.8) | 12 (12.9) | |
Others | 15 (18.8) | 20 (21.5) | |
Seizure duration before treatment, min | 42.0 (21, 90) | 60 (30, 80) | 0.25 |
Others were causes other than those listed, which each physician was unable to categorise. Continuous variables with a normal distribution are expressed as the mean±SD and compared using the Student’s t-test. Non-parametric continuous variables are expressed as medians (IQRs) and compared using the Mann-Whitney U test. Categorical variables are expressed as n (%) and compared using the χ2 test.
FPHT, fosphenytoin; LEV, levetiracetam.