Table 1

Comparison of clinical characteristics between patients with MMD and AS-MMV

Before PSMAfter PSM
All cases
(n=1173)
MMD
(n=881)
AS-MMV (n=292)P valueAll cases
(n=572)
MMD
(n=286)
AS-MMV (n=286)P value
Gender
 Male575 (49.0%)417 (47.3%)158 (54.1%)0.05309 (54%)157 (54.9%)152 (53.1%)0.737
 Female598 (51.0%)464 (52.7%)134 (45.9%)263 (46%)129 (45.1%)134 (46.9%)
Age, years42.4±11.041.7±10.844.5±11.3<0.00143.7±11.244.1±11.143.3±11.20.408
Hypertension486 (41.4%)345 (39.2%)141 (48.3%)0.007268 (46.9%)133 (46.5%)135 (47.2%)0.933
Hyperlipidaemia300 (25.6%)187 (21.2%)113 (38.7%)<0.001210 (36.7%)103 (36.1%)107 (37.4%)0.795
Diabetes145 (12.4%)91 (10.3%)54 (18.5%)<0.00189 (15.6%)41 (14.3%)48 (16.8%)0.489
Smoking370 (31.5%)271 (30.8%)99 (33.9%)0.345183 (32.0%)89 (31.1%)94 (32.9%)0.720
PCA involvement513 (43.7%)385 (43.7%)128 (43.8%)1.000243 (42.5%)118 (41.3%)125 (43.7%)0.612
Bilateral involvement999 (85.2%)742 (84.2%)257 (88.0%)0.128547 (95.6%)272 (95.1%)275 (96.2%)0.683
Suzuki stage
 <IV257 (21.9%)191 (21.7%)66 (22.6%)0.744130 (22.7%)65 (22.7%)65 (22.7%)1.000
 ≥IV916 (78.1%)690 (78.3%)226 (77.4%)442 (77.3%)221 (77.3%)221 (77.3%)
Initial clinical presentation
 TIA/infarction854 (72.8%)645 (73.2%)209 (71.6%)0.596405 (70.8%)199 (69.6%)206 (72.0%)0.581
 Haemorrhage163 (13.9%)116 (13.2%)47 (16.1%)0.206101 (17.7%)55 (19.2%)46 (16.1%)0.380
 Others156 (13.3%)120 (13.6%)36 (12.3%)0.62066 (11.5%)32 (11.2%)34 (11.9%)0.896
Operation or not964 (82.2%)735 (83.4%)229 (78.4%)0.064460 (80.4%)237 (82.9%)223 (78.0%)0.085
  • AS-MMV, atherosclerosis-associated moyamoya vasculopathy; MMD, moyamoya disease; PCA, posterior cerebral artery; PSM, propensity score matching; TIA, transient ischaemic attack.