Table 3

Characteristics of cohort studies included in qualitative synthesis

Author (ref)	LTPA measure	Country	First year observation	Follow-up (months, n)	Subjects (n)	Women (n - %)	Outcome measure	No. stroke cases	AGE (min-max)	Mean age	Race/ethnicity	Narrative summary
Hamer et al 20*	Q	UK	1994–2008	112.8	65 093	35 541 (54.6 %)	National Health Service Central Registry diagnosis	633	40	58±12.0	Caucasian	LTPA stratified into quintiles. Decreased risk of stroke in second, fourth, and fifth, but not in third quintile compared with the first one
Hooker et al 31	A	USA	2003	88.8	7607	4145 (54.5%)	Patient contact, medical records review for clinical definition.	286	N.A.	63.4±8.0	Mixed	LTPA stratified into tertiles. Moderate-to-vigorous LTPA linked to decreased risk of stroke in both second and third tertiles compared with the first one. Low-intensity LTPA not linked to decreased risk of stroke in either the second or third tertiles compared with the first one
Hummel et al34	Q	Sweden	1997	214.8	31 580	20 855 (66.0%)	ICD codes on medical discharge reports	707	N.A.	N.A.	Caucasian	LTPA stratified into tertiles. No decreased risk of stroke in the second or third tertiles compared with the first one
Jeong et al 36	Q	South Korea	2002–2013	43.2	336 326	164 645 (48.9%)	ICD codes on medical discharge reports	2213	N.A.	N.A.	Asian	LTPA stratified according to frequency. Any LTPA frequency linked to decreased risk of stroke compared with no activity, except from the highest one (‘almost every day’)
Kim et al 35	Q	South Korea	2002–2015	156.0	257 854	49.5%	ICD 10 codes on hospital and death reports	16 134	N.A.	50.7±8.7	Asian	LTPA stratified according to frequency. Any LTPA frequency linked to decreased risk of stroke compared with no activity
MacDonald et al†33	Q	France	1990	194.4	95 169	95 169 (100%)	Self-reporting followed by analysis of medical reports by experts	592	N.A.	51.2±6.7	N.A.	LTPA stratified into tertiles. Decreased risk of stroke in the second, but not in the third tertile of LTPA compared with the first one
Wannamethee et al 32	Q	UK	N.A.	114.0	7735	0	ICD codes on death reports and clinical diagnosis on medical records.	128	40–59	N.A.	Caucasian	LTPA categorised in six levels. Decreased risk of stroke only in the highest level of LTPA compared with the lowest level

*The cohort data expressed in tertiles.
†It includes three different analyses of the same cohort.
A, accelerometer; I, in person interview; ICD-9, International Classification of Diseases, 9^th Edition; ICD-10, International Classification of Diseases, 10^th Edition; N.A, not available; Q, self-reported questionnaire; T, telephone interview.