Table 2

Baseline clinical parameters in non-motor, motor and levodopa response strata

	Non-Motor Symptom Scale
	‘Mild to moderate’			‘Severe’			‘Very severe’
	(≤40)			(41–70)			(≥71)
	n	Mean	SD	n	Mean	SD	n	Mean	SD	P value
PDQ-8 Summary Index	56	26.2	12.3	50	33.7	13.3	60	41.4	15.5	<0.001***
	Hoehn and Yahr Scale
	‘Minimal to mild’			‘Moderate’			‘Severe’
	(≤ 2.5)			(3)			(≥ 4)
	n	Mean	SD	n	Mean	SD	n	Mean	SD	P value
PDQ-8 Summary Index	96	31.3	14.5	48	37.2	14.7	19	37.3	16.7	0.105
	Levodopa challenge test response
	‘Low’			‘Partial’			‘Full’
	(<33%)			(33%–50%)			(>50%)
	n	Mean	SD	n	Mean	SD	n	Mean	SD	P value
PDQ-8 Summary Index	43	34.2	14.1	55	34.1	15.5	66	33.7	15.8	0.947

Kruskal-Wallis tests were performed for independent samples for between-strata analyses of baseline parameters. Multiple comparisons (three strata) were corrected with the Bonferroni method.
Bold font highlights significant results.
***p<0.001.
PDQ-8, 8-item Parkinson’s Disease Questionnaire.