Table 1

Motor examination scores

BaselineFollow-upChange
OFF medication state
MDS-UPDRS ME, mean±SD51.4±16.525.2±14.5−26.2±16
 Tremor, median (IQR)*5.5 (11)0 (2)−3.5 (8)
 Rigidity, median (IQR)†8 (6)0 (3)−6 (6)
 Bradykinesia, median (IQR)‡22 (12)12 (9)−9 (9)
 PIGD, median (IQR)§3 (4)1 (2)−1 (3)
ON medication state
MDS-UPDRS ME, mean±SD19.1±10.815.9±10.6−3.2±9.3
 Tremor, median (IQR)0 (0)0 (0)0 (0)
 Rigidity, median (IQR)1 (3)0 (1)0 (2)
 Bradykinesia, median (IQR)9 (8)7 (9)−2 (7)
 PIGD, median (IQR)1 (2)0 (1)0 (1)

  • *Tremor score was calculated from MDS-UPDRS ME items 3.15–3.18.

  • †Rigidity score is MDS-UPDRS ME item 3.3.

  • ‡Bradykinesia score was calculated from MDS-UPDRS ME items 3.4–3.8.

  • §PIGD is calculated from MDS-UPDRS ME items 3.10–3.12.

  • MDS-UPDRS ME, Movement Disorder Society–Unified Parkinson’s disease Severity Rating Scale Motor Examination; PIGD, postural instability and gait disturbance.