Summary of the matching features and the main outcomes
| Patients | Matched controls | P value | |
| At disease start | |||
| Total, n | 65 | 650 | |
| Mean age at disease start (years, (SD)) | 45.3 (19.0) | 45.3 (18.9) | |
| Female, n (%) | 58 (89.2) | 580 (89.2) | |
| Education, n (%) | |||
| Lower secondary | 22 (33.8) | 230 (35.4) | |
| Upper secondary | 22 (33.8) | 217 (33.4) | |
| Post secondary | 15 (23.1) | 132 (20.3) | |
| Socioeconomic status at disease start, n (%) | |||
| Own business | <3 | 15 (2.3) | |
| Employee | 24 (36.9) | 297 (45.7) | |
| Unemployed or welfare benefit | <3 | 46 (7.1) | |
| Leave of absence (sick leave or parental leave) | 5 (7.7) | 6 (0.9) | |
| Educational support | 0 (0.0) | 49 (7.5) | |
| Other | 25 (38.5) | 222 (34.2) | |
| Outcomes | |||
| Annual median income | |||
| Total, n | 35 | 402 | |
| 1-year before index year in 2015-indexed Euro (median, IQR) | 32 928 (10 222 to 42 521) | 32 970 (9256 to 46 721) | 0.38 |
| At index year in 2015-indexed Euro (median, IQR) | 22 631 (4492 to 44 201) | 34 627 (10 963 to 47 497) | 0.14 |
| At 1 year after index year in 2015-indexed Euro (median, IQR) | 13 285 (139 to 36 336) | 33 035 (6870 to 45 978) | 0.04 |
| At 5 years after index year in 2015-indexed Euro (median, IQR) | 276 (0 to 23 691) | 22 141 (0 to 42 986) | 0.03 |
| Disability pension | |||
| Total, n | 65 | 650 | |
| At baseline, n (%) | 6 (9.2) | 47 (7.2) | 0.56 |
| At follow-up, n (%) | 24 (36.9) | 91 (14.0) | 0.00 |
| ‘Flexjob’ | |||
| Total, n | 65 | 650 | |
| At baseline, n (%) | 0 (0.0) | 13 (2.0) | 0.25 |
| At follow-up, n (%) | 11 (16.9) | 28 (4.3) | 0.00 |
| Civil status | |||
| Total, n | |||
| Married/regular partnership | 65 | 650 | |
| At baseline, n (%) | 32 (49.2) | 343 (52.8) | 0.59 |
| At follow-up, n (%) | 34 (52.3) | 342 (52.6) | 0.96 |
| Single, divorced or widow | |||
| At baseline, n (%) | 33 (50.8) | 307 (47.2) | 0.59 |
| Single or widow at follow-up, n (%) | 19 (29.2) | 203 (31.2) | 0.74 |
| Divorced at follow-up, n (%) | 11 (16.9) | 104 (16.0) | 0.84 |
<3: due to the General Data Protection Regulation, extracting precise microdata when the number of cases is below three are not allowed.