Association between change in intraventricular haemorrhage volume and outcomes
| Outcome | Modified Rankin Scale score, 4–6 at 12 months* | Mortality at 12 months* | ||
| OR (95% CI) | P value† | OR (95% CI) | P value† | |
| Unadjusted analysis | ||||
| Entire cohort (unadjusted) | 0.99 (0.95 to 1.05) | 0.87 | 1.00 (0.93 to 1.09) | 0.92 |
| Multivariable analysis | ||||
| Entire cohort (adjusted) | 1.02 (0.96 to 1.08) | 0.61 | 0.99 (0.92 to 1.06) | 0.77 |
| Admission ICH volume (mL) | ||||
| <45 | 1.01 (0.92 to 1.11) | 0.79 | 0.95 (0.87 to 1.03) | 0.20 |
| ≥45 | 1.02 (0.93 to 1.12) | 0.68 | 1.03 (0.93 to 1.14) | 0.52 |
| Deep ICH location | 0.98 (0.88 to 1.09) | 0.69 | 0.97 (0.89 to 1.06) | 0.46 |
| Lobar ICH location | 1.04 (0.96 to 1.14) | 0.42 | 1.05 (0.94 to 1.18) | 0.38 |
*Model was adjusted for age, sex, black race, Glasgow Coma Scale at randomisation, admission parenchymal ICH volume, parenchymal ICH location and treatment randomisation arm.
†P<0.05 was considered statistically significant.
ICH, intracerebral haemorrhage