ALS

Risk factors for cognitive impairment in amyotrophic lateral sclerosis: a systematic review and meta-analysis
Tianmi Yang, Yanbing Hou, Chunyu Li, Bei Cao, Yangfan Cheng, Qianqian Wei, Lingyu Zhang, Huifang Shang

Journal of Neurology, Neurosurgery & Psychiatry Jul 2021, 92 (7) 688-693; DOI: 10.1136/jnnp-2020-325701
Extensive heterogeneity in patients with ALS with mutations in SOD1 in France
Peter Munch Andersen

Journal of Neurology, Neurosurgery & Psychiatry Apr 2021, jnnp-2021-326553; DOI: 10.1136/jnnp-2021-326553
Hemiplegic-type ALS shows a strong correlation between upper, lower motor neuron degeneration and pTDP-43 pathology
Nilo Riva, Angelo Quattrini

Journal of Neurology, Neurosurgery & Psychiatry Apr 2021, jnnp-2021-326512; DOI: 10.1136/jnnp-2021-326512
Plasma microRNA signature as biomarker for disease progression in frontotemporal dementia and amyotrophic lateral sclerosis
Ramita Dewan, Bryan J Traynor

Journal of Neurology, Neurosurgery & Psychiatry May 2021, 92 (5) 458; DOI: 10.1136/jnnp-2020-325478
Unravelling the clinical spectrum and the role of repeat length in C9ORF72 repeat expansions
Emma L. van der Ende, Jazmyne L. Jackson, Adrianna White, Harro Seelaar, Marka van Blitterswijk, John C. Van Swieten

Journal of Neurology, Neurosurgery & Psychiatry May 2021, 92 (5) 502-509; DOI: 10.1136/jnnp-2020-325377
Reconsidering the revised amyotrophic lateral sclerosis functional rating scale for ALS clinical trials
Adriaan D de Jongh, Leonard H van den Berg, Ruben P A van Eijk

Journal of Neurology, Neurosurgery & Psychiatry May 2021, 92 (5) 569-570; DOI: 10.1136/jnnp-2020-325253
Isolated homozygous R217X OPTN mutation causes knock-out of functional C-terminal optineurin domains and associated oligodendrogliopathy-dominant ALS–TDP
Matthew Nolan, Paola Barbagallo, Martin R Turner, Michael John Keogh, Patrick F Chinnery, Kevin Talbot, Olaf Ansorge

Journal of Neurology, Neurosurgery & Psychiatry Mar 2021, jnnp-2020-325803; DOI: 10.1136/jnnp-2020-325803
The stage is set for a new trial end point in ALS
Christopher J McDermott

Journal of Neurology, Neurosurgery & Psychiatry Feb 2021, 92 (2) 117; DOI: 10.1136/jnnp-2020-325158
Cerebrospinal fluid phosphorylated neurofilament heavy chain and chitotriosidase in primary lateral sclerosis
Federico Verde, Gloria Zaina, Caterina Bodio, Maria Orietta Borghi, Davide Soranna, Silvia Peverelli, Nicola Ticozzi, Claudia Morelli, Alberto Doretti, Stefano Messina, Luca Maderna, Claudia Colombrita, Valentina Gumina, Cinzia Tiloca, Pier Luigi Meroni, Antonella Zambon, Antonia Ratti, Vincenzo Silani

Journal of Neurology, Neurosurgery & Psychiatry Feb 2021, 92 (2) 221-223; DOI: 10.1136/jnnp-2020-324059
TDP-43 proteinopathies: a new wave of neurodegenerative diseases
Eva Maria Johanna de Boer, Viyanti K Orie, Timothy Williams, Mark R Baker, Hugo M De Oliveira, Tuomo Polvikoski, Matthew Silsby, Parvathi Menon, Mehdi van den Bos, Glenda M Halliday, Leonard H van den Berg, Ludo Van Den Bosch, Philip van Damme, Matthew C Kiernan, Michael A van Es, Steve Vucic

Journal of Neurology, Neurosurgery & Psychiatry Jan 2021, 92 (1) 86-95; DOI: 10.1136/jnnp-2020-322983

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