biomarkers

J05 Interim results from cohort 1 of the double-blind, dose-escalation phase I/II clinical trial of amt-130 (HD-genetrx-1) for early-stage huntington’s disease (HD)
Erin Furr Stimming, Victor Sung, Claudia Testa, Sandra Kostyk, Christopher A Ross, Ali Samii, Michael D Geschwind, Deborah Hall, Praveen Dayalu, Russell Lonser, Brad Elder, Paul S Larson, David L Cooper, Marcie Clarkin, Talaha M Ali, Ricardo E Dolmetsch, on behalf of the AMT-130-01 Investigators

Journal of Neurology, Neurosurgery & Psychiatry Sep 2022, 93 (Suppl 1) A95; DOI: 10.1136/jnnp-2022-ehdn.255
J11 Pridopidine exerts beneficial effects in preclinical models and in clinical trials via activation of the sigma-1 receptor, in a biphasic manner
Michal Geva, Deniz Akinc Abdulhayoglu, Shao-Ming Wang, Noga Gershoni-Emek, Bruno Boulanger, Y Paul Goldberg, Tsung-Ping Su, Michael R Hayden

Journal of Neurology, Neurosurgery & Psychiatry Sep 2022, 93 (Suppl 1) A98; DOI: 10.1136/jnnp-2022-ehdn.261
E14 Neuroimaging biomarkers in Huntington’s disease
Nadine A van de Zande, Eidrees Ghariq, Jeroen HJM de Bresser, Raymund AC Roos, Susanne T de Bot

Journal of Neurology, Neurosurgery & Psychiatry Sep 2022, 93 (Suppl 1) A36; DOI: 10.1136/jnnp-2022-ehdn.90
D04 Challenges and advances in cerebrospinal fluid HTT detection: in support of relative quantification
Rachel J Harding, Yuanyun Xie, Nalini Potluri, Cheryl H Arrowsmith, Blair R Leavitt, Douglas Langbehn, Amber L Southwell

Journal of Neurology, Neurosurgery & Psychiatry Sep 2022, 93 (Suppl 1) A21; DOI: 10.1136/jnnp-2022-ehdn.60
D03 Novel bioassays to detect soluble and aggregated isoforms of the huntingtin protein on three technology platforms
Christian Landles, Georgina F Osborne, Rebecca E Milton, Alexandre Jean, Stuart McLarnon, Chuangchuang Zhang, Wenzhen Duan, Gillian P Bates

Journal of Neurology, Neurosurgery & Psychiatry Sep 2022, 93 (Suppl 1) A21; DOI: 10.1136/jnnp-2022-ehdn.59
D12 Faulty linear and back-splicing in Huntington’s disease: novel players in the pathologic process hint at innovative RNA biomarkers
Miguel Pellegrini, Dilara Ayyildiz, Guendalina Bergonzoni, Alan Monziani, Takshashila Tripathi, Jessica Döring, Giulia Cardamone, Emanuela Kerschbamer, Francesca Di Leva, F Perrone, MP Abruzzese, LC Busi, Rosanna Asselta, Elia Pennati, Luisa Donini, Jacopo Zasso, Luciano Conti, Vanessa C Wheeler, Christoph Dieterich, Silvano Piazza, Erik Dassi, Ferdinando Squitieri, Marta Biagioli

Journal of Neurology, Neurosurgery & Psychiatry Sep 2022, 93 (Suppl 1) A24; DOI: 10.1136/jnnp-2022-ehdn.68
D17 Extracellular vesicles biology in huntington disease
Andreas Neueder, Philipp Nitzschner, Ronja Wagner, Julia Hummel, Franziska Hoschek, Maximilian Wagner, Alshaimaa Abdelmoez, Björn von Einem, Sarah Tabrizi, Michael Orth

Journal of Neurology, Neurosurgery & Psychiatry Sep 2022, 93 (Suppl 1) A26; DOI: 10.1136/jnnp-2022-ehdn.73
D21 Analysis of blood and CSF biomarkers in mouse models of Huntington’s disease
Marie K Bondulich, Lauren M Byrne, Arzo Iqbal, Iulia M Nita, María Cañibano-Pico, Jemima M Phillips, Edward Wild, Gillian P Bates

Journal of Neurology, Neurosurgery & Psychiatry Sep 2022, 93 (Suppl 1) A27; DOI: 10.1136/jnnp-2022-ehdn.77
E05 Longitudinal evaluation of magnetic resonance spectroscopy metabolites as biomarkers in Huntington’s disease
Alexander J Lowe, Filipe B Rodrigues, Marzena Arridge, Enrico De Vita, Eileanoir B Johnson, Rachael I Scahill, Lauren M Byrne, Rosanna Tortelli, Amanda Heslegrave, Henrik Zetterberg, Edward J Wild

Journal of Neurology, Neurosurgery & Psychiatry Sep 2022, 93 (Suppl 1) A29-A32; DOI: 10.1136/jnnp-2022-ehdn.82
F01 Development of the huntington’s disease integrated staging system (HD-ISS)
Sarah Tabrizi, Scott Schobel, Emily Gantman, Alexandra Mansbach, Beth Borowsky, Pavlina Konstantinova, Tiago Mestre, Ariana Mullin, Jennifer Panagoulias, Klaus Romero, Christopher A Ross, Sudhir Sivakumaran, Emily Turner, Maurice Zauderer, Jeff Long, Cristina Sampaio, Huntington’s Disease Regulatory Science Consortium (HD-RSC)

Journal of Neurology, Neurosurgery & Psychiatry Sep 2021, 92 (Suppl 1) A19-A20; DOI: 10.1136/jnnp-2021-EHDN.44

Main menu

biomarkers

Pages

Log in using your username and password

Main menu

Log in using your username and password

You are here

biomarkers

Pages