biomarkers

I05 Sustained mutant huntingtin lowering in the brain and cerebrospinal fluid of huntington disease minipigs mediated by AAV5-MIHTT gene therapy
Astrid Valls, Cynthia Brouwers, Roberta Pintauro, Jolanda Snapper, Bozena Bohuslavova, Marina Sogorb-Gonzalez, Valentina Fodale, Alberto Bresciani, Zdenka Ellederova, Bas Blits, Jan Motlik, Sander van Deventer, Melvin Evers, Pavlina Konstantinova

J Neurol Neurosurg Psychiatry Sep 2018, 89 (Suppl 1) A89-A90; DOI: 10.1136/jnnp-2018-EHDN.241
A31 The development of translational biomarkers of neuroinflammation in a mouse model of huntington’s disease
Laura Riggall, Bernard Siow, Xavier Golay, Gillian Bates

J Neurol Neurosurg Psychiatry Sep 2018, 89 (Suppl 1) A11; DOI: 10.1136/jnnp-2018-EHDN.29
F22 Robust biomarkers of huntington’s disease progression: observations from the track-hd, predict-hd and image-hd studies
Peter A Wijeratne, Eileanoir B Johnson, Sarah Gregory, Amrita Mohan, Cristina Sampaio, Rachael I Scahill, Sarah J Tabrizi, Daniel C Alexander

J Neurol Neurosurg Psychiatry Sep 2018, 89 (Suppl 1) A47; DOI: 10.1136/jnnp-2018-EHDN.126
A11 Skin fibroblasts from huntington´s disease patients show distinct signature of MIRNAS expression along disease progression
Veronica Brito, Ruben Fernandez-Santiago, Mario Ezquerra, Esther Sieiro, Jesus Perez-Perez, Jaime Kulisevsky, Silvia Gines

J Neurol Neurosurg Psychiatry Sep 2018, 89 (Suppl 1) A4-A5; DOI: 10.1136/jnnp-2018-EHDN.11
A07 A comparative study on blood and brain hd signatures: comparing mouse and human hd gene expression data
Eleni Mina, Lodewijk Toonen, Elsa Kuijper, Melvin Evers, Marco Roos, Willeke van Roon-Mom

J Neurol Neurosurg Psychiatry Sep 2018, 89 (Suppl 1) A3; DOI: 10.1136/jnnp-2018-EHDN.7
Imaging the pathoanatomy of amyotrophic lateral sclerosis in vivo: targeting a propagation-based biological marker
Jan Kassubek, Hans-Peter Müller, Kelly Del Tredici, Dorothée Lulé, Martin Gorges, Heiko Braak, Albert C Ludolph

J Neurol Neurosurg Psychiatry Apr 2018, 89 (4) 374-381; DOI: 10.1136/jnnp-2017-316365
Baseline prevalence and longitudinal evolution of non-motor symptoms in early Parkinson’s disease: the PPMI cohort
Tanya Simuni, Chelsea Caspell-Garcia, Christopher S Coffey, Daniel Weintraub, Brit Mollenhauer, Shirley Lasch, Caroline M Tanner, Danna Jennings, Karl Kieburtz, Lana M Chahine, Kenneth Marek

J Neurol Neurosurg Psychiatry Jan 2018, 89 (1) 78-88; DOI: 10.1136/jnnp-2017-316213
Tracking and predicting disease progression in progressive supranuclear palsy: CSF and blood biomarkers
Edwin Jabbari, Henrik Zetterberg, Huw R Morris

J Neurol Neurosurg Psychiatry Oct 2017, 88 (10) 883-888; DOI: 10.1136/jnnp-2017-315857
Longitudinal assessment of excessive daytime sleepiness in early Parkinson’s disease
Amy W Amara, Lama M Chahine, Chelsea Caspell-Garcia, Jeffrey D Long, Christopher Coffey, Birgit Högl, Aleksandar Videnovic, Alex Iranzo, Geert Mayer, Nancy Foldvary-Schaefer, Ron Postuma, Wolfgang Oertel, Shirley Lasch, Ken Marek, Tanya Simuni

J Neurol Neurosurg Psychiatry Aug 2017, 88 (8) 653-662; DOI: 10.1136/jnnp-2016-315023
I15 Electronic clinical dashboard for assessing symptomatic progression in huntington’s disease
Thomas Walker, Christopher Kipps, Boyd Ghosh

J Neurol Neurosurg Psychiatry Sep 2016, 87 (Suppl 1) A64; DOI: 10.1136/jnnp-2016-314597.180

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