Modulation of the Lexical–Semantic Network by Auditory Semantic Priming: An Event-Related Functional MRI Study

doi:10.1006/nimg.2002.1316

NeuroImage

Volume 17, Issue 4, December 2002, Pages 1761-1772

https://doi.org/10.1006/nimg.2002.1316 Get rights and content

Abstract

The current event-related fMRI study specifies the neuroanatomical correlates of semantic priming and differences in semantic relation types using an auditory primed lexical decision task (LDT). Word pairs consisted of different relation types, associations (key–chain), pure categorical relations (cow–dog), and unrelated words (table–window), as well as word–pseudoword (way–tinne) and pseudoword–pseudoword (ahurn–döva) pairs. The factor lexical status, i.e., the processing of words compared to pseudowords, was associated with activation in the middle temporal gyri and the left striatum. The factor relatedness, i.e., the contrast between unrelated and related target words, was associated with increased activation of the left inferior frontal gyrus, the deep frontal operculum bilaterally, and the middle frontal gyri. A direct contrast between the two semantic relation types indicated that the processing of purely categorical compared to associative information recruits the right precuneus, the isthmus gyrus cinguli, and the cuneus, suggesting more effortful processing of the former information type. The present data show that the factors lexical status, semantic relatedness, and type of semantic relation in a primed LDT modulate the hemodynamic response in cerebral areas that subserve auditory word recognition and subsequent lexical–semantic processing.

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As reported in other studies, indirect semantic priming, when requiring postlexical or retrospective processing, seems to involve activations in the right hemisphere for both related and unrelated targets (Koivisto, 1998; Silva-Pereyra et al. 1999; Sass et al., 2009). This was the case for PSEUDO, where additionally to rINSa and rIFG, this latter involved in inhibition during executive control tasks (Hampshire et al., 2010; Aron et al., 2014), presented rMTG activity, an area that has been associated with semantic integration in diverse modalities (Kotz et al., 2002; Sass et al., 2009), and for NOREL, with a cluster in rINSa and precuneus in the current findings. NOREL condition presented a cluster of activation in the left fusiform gyrus, which has been largely associated with automatic semantic processing such as mapping word-form on to meaning (Wheatley et al., 2005;Sass et al., 2009; Kuperberg et al., 2019), reflecting a lexical-semantic analysis of each NOREL target of its own, without taking into consideration the previous prime nor any relation between prime-target.
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Regular ArticleModulation of the Lexical–Semantic Network by Auditory Semantic Priming: An Event-Related Functional MRI Study

Abstract

NeuroImage

NeuroImage

Neuropsychology

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Brain Lang.

NeuroImage

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Cognit. Psychol.

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Neurosci. Lett.

NeuroImage

Neuropsychologia

Trends Cognit. Sci.

Brain Lang.

Brain Lang.

Influence of case type, word frequency, and exposure duration on visual word recognition

J. Exp. Psychol. Hum. Percept. Perform.

Auditory and visual semantic priming using different stimulus onset asynchronies: An event-related brain potential study

Psychophysiology

Summation priming and coarse semantic coding in the right hemisphere

J. Cognit. Neurosci.

Functional magnetic resonance imaging of the human auditory cortex

Ann. Neurol.

Function of the left planum temporale in auditory and linguistic processing

Brain

Human brain language areas identified by functional magnetic resonance imaging

J. Neurosci.

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J. Cognit. Neurosci.

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Cereb. Cortex

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J. Magn. Reson. Imaging

Explicit and implicit processing of words and pseudowords by adult developmental dyslexics—A search for Wernicke's Wortschatz?

Brain

Dissociation of human prefrontal cortical area across different speech production tasks and gender groups

J. Neurophysiol.

Functional MRI evidence for the role of frontal and inferior temporal cortex in amodal components of priming

Brain

Auditory and visual word processing studied with fMRI

Hum. Brain Mapp.

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Psychol. Rev.

Selective averaging of rapidly presented individual trials using fMRI

Hum. Brain Mapp.

Primed lexical decision: Combined effects of the proportion of related prime-target pairs and the stimulus onset asynchrony of prime and target

Q. J. Exp. Psychol.

Semantic encoding and retrieval in the left inferior prefrontal cortex: A functional MRI study of task difficulty and process specificity

J. Neurosci.

The anatomy of phonological and semantic processing in normal subjects

Brain

Functional magnetic resonance imaging assessment of the human brain auditory cortex response to increasing word presentation rates

J. Neurophysiol.

fMRI evidence for dual routes to the mental lexicon in visual word recognition

J. Cognit. Neurosci.

Phonology, semantics, and the role of the left inferior prefrontal cortex

Hum. Brain Mapp.

PET studies on auditory and phonological processing: Effects of stimulus characteristics and task demands

J. Cognit. Neurosci.

Neuroimaging studies of word reading

Proc. Natl. Acad. Sci. USA

Brain activity during memory retrieval: The influence of imagery and semantic cueing

Brain

Accessing the mental lexicon

Regular Article
Modulation of the Lexical–Semantic Network by Auditory Semantic Priming: An Event-Related Functional MRI Study