Summary
We report a 69-year-old female with cerebral and cerebellar symptomatology of 15-month duration. At autopsy, both panencephalopathic Creutzfeldt-Jakob and plaque-predominant Alzheimer diseases were found. Plaque amyloid was exclusively of the β/A4 type, but abundant abnormal protease-resistant protein was identified by Western blot analysis of brain extracts.
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Powers, J.M., Liu, Y., Hair, L.S. et al. Concomitant Creutzfeldt-Jakob and Alzheimer diseases. Acta Neuropathol 83, 95–98 (1991). https://doi.org/10.1007/BF00294437
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DOI: https://doi.org/10.1007/BF00294437