Skip to main content
Log in

Intravascular lymphoma simulating vasculitis

  • Case Report
  • Published:
Rheumatology International Aims and scope Submit manuscript

Abstract

The case history of a patient with intravascular lymphoma (IL) is reported. Signs of a systemic illness including fever, muscular weakness, telangiectasias, nephrotic syndrome, and neurologic manifestation suggested vasculitis. Cyclophosphamide treatment produced almost complete remission, but the patient died of respiratory failure 13 months after presentation due to lung involvement. The diagnosis was not revealed until postmortem examination. The differential diagnosis of IL is provided.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

Similar content being viewed by others

References

  1. Pfleger L, Tappeiner J (1959) Zur Kenntnis der systematisierten Endotheliomatose der cutanen Blutgefäße. Hautarzt 10:359–363

    Google Scholar 

  2. Domizio P, Hall PA (1959) Angiotropic large cell lymphoma (ALCL): morphological, immunohistochemical and genotypic studies with analysis of previous reports. Hematol Oncol 7:195–206

    Google Scholar 

  3. Wick MR, Banks PM, McDonald TJ (1981) Angioendotheliomatosis of the nose with fatal systemic dissemination. Cancer 48:2510–2517

    Google Scholar 

  4. Arnn ET, Yam LT, Li C (1983) Systemic angioendotheliomatosis presenting with hemolytic anemia. Am J Clin Pathol 80: 246–251

    Google Scholar 

  5. Otrakji CL, Voigt W, Amador A, Nadji M, Gregorios JB (1988) Malignant angioendotheliomatosis — a true lymphoma: a case of intravascular malignant lymphomatosis studied by southern blot hybridization analysis. Hum Pathol 19:475–478

    Google Scholar 

  6. Wick MR, Mills SE, Scheithauer BW, Cooper PH, Davit MA, Parkinson K (1986) Reassessment of malignant “angioendotheliomatosis”. Evidence in favour of its reclassification as “intravascular lymphomatosis”. Am J Surg Pathol 10:112–123

    Google Scholar 

  7. Bhawan J, Wolff SM, Ucci AA, Bhan AK (1985) Malignant lymphoma and malignant angioendotheliomatosis: one disease. Cancer 55:570–576

    Google Scholar 

  8. Yousem SA, Colby TV (1990) Intravascular lymphomatosis presenting in the lung. Cancer 65:349–353

    Google Scholar 

  9. Glass J, Hochberg FH, Miller DC (1993) Intravascular lymphomatosis — a systemic disease with neurologic manifestations. Cancer 71:3156–3164

    Google Scholar 

  10. Lightfoot RW, Michel BA, Bloch DA, Hunder GD, Zvaifler NJ, McShane DJ, Arend WP, Calabrese LH, Levitt RY, Lie JT Masi AT, Mills JA, Stevens MB, Wallace SL (1990) The American College of Rheumatology 1990 criteria for the classification of polyarteritis nodosa. Arthritis Rheum 33:1088–1093

    Google Scholar 

  11. Kao NL, Broy S, Tillawi I (1992) Malignant angioendotheliomatosis mimicking systemic necrotizing vasculitis. J Rheumatol 19:1133–1135

    Google Scholar 

  12. Lie JT (1992) Malignant angioendotheliomatosis (intravascular lymphomatosis) clinically simulating primary angiitis of the central nervous system. Arthritis Rheum 35:831–834

    Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Rights and permissions

Reprints and permissions

About this article

Cite this article

Walker, U.A., Herbst, E.W., Ansorge, O. et al. Intravascular lymphoma simulating vasculitis. Rheumatol Int 14, 131–133 (1994). https://doi.org/10.1007/BF00300816

Download citation

  • Received:

  • Accepted:

  • Issue Date:

  • DOI: https://doi.org/10.1007/BF00300816

Key words

Navigation