Summary
An intra vitam diagnosis of Baló's concentric sclerosis in a 39-year-old male is described. To our knowledge this is the first reported case of ante-mortem diagnosis based solely on magnetic resonance imaging (MRI) findings. MRI showed features unique to this process. After high-dose intravenous therapy with prednisone, the clinical symptoms improved, and MRI showed marked changes of the concentric lesions.
References
Baló J (1928) Encephalitis periaxialis concentrica. Arch Neurol Psychiatry 19:242–264
Courville CB (1970) Concentric sclerosis. In: Vinken P, Bruyn GW (eds) Handbook of clinical neurology, vol 9. North Holland, Amsterdam, pp 437–451
Garbern J, Spence AM, Alvord EC (1986) Baló's concentric demyelination diagnosed premortem. Neurology 36:1610–1614
Marburg O (1906) Die sogenannte „akute multiple Sklerose“ (Encephalomyelitis periaxialis scleroticans). Jahrb Neurol Psychiatr 27:213–312
Nagara H, Inoue T, Koga T, Kitagnchi T, Tateishi J, Goto I (1987) Formalin fixed brains are useful for magnetic resonance imaging (MRI) study. J Neurol Sci 81:67–77
Author information
Authors and Affiliations
Rights and permissions
About this article
Cite this article
Spiegel, M., Krüger, H., Hofmann, E. et al. MRI study of Baló's concentric sclerosis before and after immunosuppressive therapy. J Neurol 236, 487–488 (1989). https://doi.org/10.1007/BF00328514
Received:
Accepted:
Issue Date:
DOI: https://doi.org/10.1007/BF00328514