Summary
Psychiatric manifestations of familial spastic paraplegia are rare and have been described only infrequently. A 35-year-old male is reported, who presented both hypomanic behaviour and gait disturbances as features of a previously undiagnosed familial spastic paraplegia. This association implies that the CNS manifestations of familial spastic paraplegia may overlap with the neurochemical or neuroanatomic substrata regulating mood.
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Jansen, P.H.P., Keyser, A. & Raes, B.C.M. Hypomanic behaviour associated with familial spastic paraplegia. Eur Arch Psychiatr Neurol Sci 238, 28–30 (1988). https://doi.org/10.1007/BF00381076
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DOI: https://doi.org/10.1007/BF00381076