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Combined central and peripheral acute demyelination

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Abstract

We describe a patient with multiple sclerosis who had a bout of central demyelination associated with an acute inflammatory demyelinating polyneuropathy. The contemporary involvement of central and peripheral nervous system due to a demyelinating disease has been reported anecdotically in humans, and can be induced experimentally in animals. It may be sustained by a common pathogenetic factor.

Sommario

In una paziente portatrice di sclerosi multipla una poussée di demielinizzazione centrale si associa ad una polineuropatia demielinizzante infiammatoria acuta. Il contemporaneo coinvolgimento del sistema nervoso centrale e periferico da parte di una malattia demielinizzante è stato riportato sporadicamente nell'uomo, ma può essere sperimentalmente indotto nell'animale e può essere sostenuto da un fattore patogenetico comune.

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Pareyson, D., Ciano, C., Fiacchino, F. et al. Combined central and peripheral acute demyelination. Ital J Neuro Sci 14, 83–86 (1993). https://doi.org/10.1007/BF02339047

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  • DOI: https://doi.org/10.1007/BF02339047

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