Pharmacologic aspects of S-adenosylmethionine: Pharmacokinetics and pharmacodynamics
References (38)
- et al.
Protective role of Sadenosyl-L-methionine on liver injury induced by D-galactosamine in rats
Biochem Pharmacol
(1978) - et al.
Protective role of S-adenosyl-L-methionine against acetaminophen-induced mortality and hepatotoxicity in mice
Biochem Pharmacol
(1979) - et al.
Influence of S-adenosyl-L-methionine on irreversible binding of ethynyl-estradiol to rat liver microsomes, and its implication in bile secretion
Biochem Pharmacol
(1979) - et al.
Ethynylestradiol-induced impairment of bile secretion in the rat: protective effects of S-adenosyl-L-methionine and its implication in estrogen metabolism
Gastroenterology
(1981) - et al.
Effect of S-adenosyl-L-methionine (SAMe) upon depressive symptoms
J Psychiatr Res
(1976) - et al.
Hypothesis: methylation and mood
Lancet
(1984) - et al.
S-Adenosylmethionine influences monoamine metabolism
Lancet
(1984) - et al.
Italian double-blind multicenter study comparing S-adenosylmethionine, naproxen, and placebo in the treatment of degenerative joint disease
Am J Med
(1987) - et al.
Pathogenesis of methionine-induced toxicity
Metabolism
(1970) - et al.
Methionineinduced hepatic coma in dogs
Am J Surg
(1975)
Evidence for impairment of transsulfuration pathway in cirrhosis
Gastroenterology
(1981)
A radioenzymatic method for S-adenosyl-L-methionine determination in biological fluids
Anal Biochem
(1984)
Transmetylation, transsulfuration and aminopropylation reactions of S-adenosyl-L-methionine “in vivo”
J Biol Chem
(1984)
Analysis of cyclooxygenase and lypoxigenase products in incubation media
Prostaglandins
(1984)
Effects of S-adenosylmethionine on human articular chondrocyte differentiation: an in vitro study
Am J Med
(1987)
Glucosamineglucans content of normal and degenerative articular cartilage of dogs
Clin Chim Acta
(1972)
The nature of the active methyl donor formed enzymatically from L-methionine and adenosintriphosphate
J Am Chem Soc
(1952)
The biochemistry of adenosylmethionine
(1977)
Biological methylation
Adv Enzymol
(1963)
Cited by (97)
Complementary and alternative medicine
2015, Rheumatology: Sixth EditionHepatobiliary Cytoprotective Agents
2012, Canine and Feline GastroenterologyImprovement of aggressive behavior and quality of life impairment following S-Adenosyl-Methionine (SAM-e) augmentation in schizophrenia
2009, European NeuropsychopharmacologySulfur-containing amino acid metabolism in parasitic protozoa
2005, Advances in ParasitologyCitation Excerpt :It has previously been demonstrated that uptake of AdoMet was three times faster than AdoMet synthesis (Goldberg et al., 1998). The fact that the serum concentration of AdoMet (70 nm; Stramentinoli, 1987) is higher than that of methionine (26 nm; Blom et al., 1989) also argues for the premise that cellular uptake of AdoMet, but not methionine, is biologically reasonable. In Trypanosoma, the AdoMet level is not regulated by the product inhibition of MAT, but probably by transporter activities (Goldberg et al., 1997, 1998).
Copyright © 1987 Published by Excerpta Medica Inc.