Clinical studyTheophylline toxicity: Clinical features of 116 consecutive cases
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2018, International Journal of Biological MacromoleculesCitation Excerpt :It is a methylxanthine drug used in therapy for bronchial asthma, emphysema, bronchitis and cardiac dyspnea [1,2]. Because of its very narrow therapeutic index, the excessive serum theophylline concentrations usually lead to serious side effects, including nausea, nervousness, tachycardia, tachyarrhythmias, seizures, and shock [3]. Generally, the therapeutic serum concentrations of theophylline are from 10 to 20 mg/L [3,4].
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