Use of esmolol to control autonomic instability of tetanus

https://doi.org/10.1016/0002-9343(91)90162-QGet rights and content
Under a Creative Commons license
open archive

Abstract

Tetanus is often accompanied by autonomic instability, rendering hemodynamic management difficult. Death is frequently secondary to an inability to control this instability. A variety of modalities have been used to stabilize the cardiovascular system, but all are not ideal. Esmolol offers theoretical advantages over other modalities. We report a case of severe tetanus in which a continuous infusion of esmolol was effective in controlling the autonomic instability.

Cited by (0)

This work was supported in part by du Pont Pharmaceuticals, which also provided the esmolol used in this patient's management.

1

Dr. Cave's current address: University Hospital, Section of Gastroenterology, Evans 201, 88 East Newton Street, Boston, Massachusetts 02118.