Immune modulation of paraneoplastic neurologic disorders

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  • Cited by (16)

    • Paraneoplastic Neurological Syndromes And Onconeural Antibodies: Clinical And Immunological Aspects

      2007, Advances in Clinical Chemistry
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      Cytokine production by the responding T cells can amplify the process by promoting blood–brain barrier permeability, upregulation of MHC class I expression, and recruitment of additional T cells [7, 19]. There are two approaches to treating PNS: eradicating the source of the antigen, that is, the tumor, through surgery, radiotherapy, or chemotherapy; and modulating the immune response such as by administering corticosteroids, intravenous immunoglobuline or azathioprine, or depleting IgG (plasma exchange) [219, 220]. The single most important factor in managing patients with PNS is identifying and treating the associated tumor as early as possible, but even with complete tumor remission, the PNS respond to varying degrees [12, 221].

    • Clinical presentation of small cell lung cancer

      2012, Principles and Practice of Lung Cancer: The Official Reference Text of the International Association for the Study of Lung Cancer (IASLC): Fourth Edition
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