Chorea as a presentation of herpes simplex encephalitis relapse
Reference (8)
- et al.
Herpes simplex encephalitis with relapse
Arch Dis Child
(1991) - et al.
Post-infectious encephalopathy after treatment of herpes simplex encephalitis with acyclovir
Pediatr Infect Dis
(1984) - et al.
Relapse of herpes simplex encephalitis
Neuropediatrics
(1987) - et al.
Herpes simplex encephalitis treatment with adenine arabinoside and cytosine arabinoside
Med J Aust
(1978)
Cited by (29)
Autoantibody-mediated diseases of the CNS: Structure, dysfunction and therapy
2018, NeuropharmacologyCitation Excerpt :Initially, a proportion of patients with HSE were found to have NMDAR-antibodies in serum and CSF but the clinical significance of these antibodies, and their time course were variable (Pruss et al., 2012). Relapsing choreoathetoid and encephalopathic symptoms in children post-HSE have long been recognised, but were not attributable to direct viral cytotoxicity (Gascon et al., 1993). The discovery that many of these children had de novo generation of NMDAR-antibodies during this relapsing choreoathetoid-encephalopathy, suggested the relapse was mediated by NMDAR-antibodies (Armangue et al., 2014b; Hacohen et al., 2014; Mohammad et al., 2014b).
Chorea and developmental regression associated with human herpes virus-6 encephalitis
2013, Pediatric NeurologyCitation Excerpt :It is possible that the first episode of febrile status epilepticus at 12 months of age was also caused by HHV-6 and that the second more severe illness was due to a reactivation of the virus. Chorea has been described as a complication of recurrent herpes simplex virus encephalitis [13-15]. It is also possible that the first episode of febrile status epilepticus was caused by a different virus and was unrelated to the second, more severe illness.
Choreoathetosis after Herpes Simplex encephalitis
2009, Anales de PediatriaThe spectrum of herpes simplex encephalitis in children
2008, European Journal of Paediatric NeurologyCitation Excerpt :Rare cases of chronic progressive encephalitic illness have also been described after a first episode of HSE.81–85 The resumption of cerebral viral replication occurring after a first episode of encephalitis has been repeatedly suspected in HSE relapses on the basis of the existence of new necrotic-hemorrhagic lesions distant from the initial site of encephalitis (Fig. 2), positive HSV PCR and/or increased alpha-IFN level in the CSF, reappearance of HSV IgG ITS, isolation of HSV from brain biopsy and/or clinical improvement under a new course of acyclovir treatment.7,9,17,30,69,70,86 In children, these relapses have been described to occur from a few days after acyclovir cessation (early relapse) to months or years after the first HSE episode (late relapse).7
Deterioration on Magnetic Resonance Imaging Despite Good Clinical Recovery After Viral Encephalitis
2008, Pediatric NeurologyCitation Excerpt :They suggested that these lesions were attributable to immune-mediated demyelination, as observed in acute disseminated encephalomyelitis. In previous reports, corticosteroids, immunoglobulin, and immunosuppressants were used with variable success to attenuate a possible immune-inflammatory reaction [10-12]. Recently, longitudinal magnetic resonance imaging studies performed in two asymptomatic children after herpes simplex encephalitis infection demonstrated the existence of self-limiting diffuse white-matter lesions, as observed in our case [4,5].
Choreoathetosis as an initial sign of relapsing of herpes simplex encephalitis
1994, Pediatric Neurology