CommentThe paradox of cholesterol and stroke
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Cited by (27)
Importance of cholesterol and cholesterol-lowering in secondary stroke prevention
2020, Bulletin de l'Academie Nationale de MedecineExtracranial carotid atherosclerotic disease
2011, Neurologia ArgentinaBaseline blood pressure, low- and high-density lipoproteins, and triglycerides and the risk of vascular events in the Stroke Prevention by Aggressive Reduction in Cholesterol Levels (SPARCL) trial
2009, AtherosclerosisCitation Excerpt :Epidemiological studies most often evaluate the relationship between total cholesterol and fatal stroke. Because most stroke patients survive and are more likely to die later from CHD rather than from another stroke [18], subjects included in these cohorts who had a nonfatal atherothrombotic stroke likely later contributed more to CHD than to stroke-related death [19]. Prospective studies evaluating the relationship between lipid parameters and the incidence of nonfatal and fatal atherothrombotic stroke in patients at risk are needed.
Lipid management in the prevention of stroke: review and updated meta-analysis of statins for stroke prevention
2009, The Lancet NeurologyCitation Excerpt :Therefore, looking at the association between cholesterol and only fatal stroke introduces a large bias because it omits 80% of stroke events that are non-fatal. More prospective, population-based studies of both fatal and non-fatal strokes are needed12 before any conclusion can be drawn on the association between cholesterol and stroke and on the causative role of cholesterol in the pathophysiology of stroke. The heterogeneity of stroke subtypes is also important.
Plasma triglyceride levels and risk of stroke and carotid atherosclerosis: A systematic review of the epidemiological studies
2009, AtherosclerosisCitation Excerpt :Blood cholesterol is a well-established risk factor for cardiovascular disease [1], whereas its relationship with fatal stroke is more controversial [2,3] despite the benefit of lipid-lowering therapy in preventing stroke events [4,5].
Statin-based therapy for primary and secondary prevention of ischemic stroke: A meta-analysis and critical overview
2020, International Journal of Stroke