Elsevier

The Lancet

Volume 322, Issues 8365–8366, 31 December 1983, Pages 1457-1459
The Lancet

Hypothesis
AETIOLOGY OF PARKINSON'S DISEASE

https://doi.org/10.1016/S0140-6736(83)90802-4Get rights and content

Abstract

It is suggested here that in most cases of Parkinson's disease the cause may be an environmental factor, possibly toxic, superimposed on a background of slow, sustained neuronal loss due to advancing age.

References (29)

  • A. Carlsson et al.

    Influence of age and time interval between death and autopsy on dopamine and 3-methoxytyramine levels in human basal ganglia

    J. Neural Transm

    (1976)
  • O. Hornykiewicz

    Dopamine (3-hydroxytyramine) and brain function

    Pharmacol Rev

    (1966)
  • Ev Evarts et al.

    Reaction time in Parkinson's disease

    Brain

    (1981)
  • H. Teravainen

    Motor system in normal aging and Parkinson's disease

  • Cited by (0)

    View full text