Focal white-matter lesions in brain of patients with inflammatory bowel disease

doi:10.1016/S0140-6736(95)90013-6

The Lancet

Volume 345, Issue 8954, 8 April 1995, Pages 897-898

https://doi.org/10.1016/S0140-6736(95)90013-6 Get rights and content

Abstract

Inflammatory bowel diseases are often associated with extra-intestinal manifestations, such as arthritis and iritis/uveitis. Using magnetic-resonance imaging we found hyperintense focal white-matter lesions in the brain in 20 of 48 (42%) patients with Crohn's disease, in 11 of 24 (46%) patients with ulcerative colitis, but in only 8 of 50 (16%) healthy age-matched controls (relative risk [95% Cl] vs controls 2·6 [1·3-5·3] and 2·9 [1·3-6·2], respectively). These findings may represent another extra-intestinal manifestation of inflammatory bowel disease.

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Focal white-matter lesions in brain of patients with inflammatory bowel disease

Abstract

Lancet

Gastroenterology

Cerebral vasculitis in Crohn's disease

Leber Magen Darm

Magnetic resonance imaging of central nervous system lesions in patients with lupus erythematosus: correlation with clinical remission and antineurofilament and anticardiolipin antibody titres

Arthritis Rheum

Gadolinium-enhanced MRI in central nervous system Behçet's disease

Neuroradiology