Elsevier

The Lancet

Volume 355, Issue 9205, 26 February 2000, Pages 725-726
The Lancet

Research Letters
Hypertensive cardiovascular damage in patients with primary autonomic failure

https://doi.org/10.1016/S0140-6736(99)05320-9Get rights and content

Summary

Patients with primary autonomic failure have left-ventricular hypertrophy probably as a result of night-time hypertension.

References (4)

There are more references available in the full text version of this article.

Cited by (138)

  • Autonomic Dysfunction and Orthostatic Hypotension

    2023, Hypertension: A Companion to Braunwald's Heart Disease
  • Synucleinopathies

    2023, Handbook of Clinical Neurology
  • Supine hypertension: A state of the art

    2022, Autonomic Neuroscience: Basic and Clinical
    Citation Excerpt :

    The subsequent, progressive loss of renal function may thus derived from increased vascular resistance and BP lability including orthostatic hypotension, which may contribute to renal hypoperfusion and a decline in eGFR (Garland et al., 2009). Left-ventricular mass index (LVMI) in patients with both central and peripheral autonomic failure and in those with essential hypertension is similar and significantly higher than normotensive controls (Maule et al., 2006; Vagaonescu et al., 2000). Various mechanisms may be postulated, such as advanced age, blood pressure load, blood pressure variability, and myocite fibrotic damage induced by mineralocorticoids (Maule et al., 2006).

  • Pharmacologic treatment of orthostatic hypotension

    2020, Autonomic Neuroscience: Basic and Clinical
View all citing articles on Scopus
View full text